Significant improvement in body contour with multiple cycles of CoolSculpting: Results of a prospective study

Abstract

Cryolipolysis is a nonsurgical body sculpting technique that uses controlled cooling for localized fat reduction. The aim of the present study was to assess whether an intensive regimen of CoolSculpting based on multiple cycles/sessions on the same body area(s) could yield greater (more clinically significant) improvements in body contour. This was a prospective analysis of consecutive, healthy, adult patients undergoing CoolSculpting in routine practice across a variety of treatment areas. Patients underwent ≤4 cycles of CoolSculpting per body area during an initial treatment session, and ≤4 further cycles 4 weeks later (if required). They were followed up for ≥12 weeks. Twenty-eight patients were enrolled (n = 26 female; mean age: 51.6 ± 9.0 years; mean body weight: 69.4 ± 13.7 kg). They were treated across 58 body areas: 48 in a single session; 10 across two sessions. The mean number of cycles per area was 2.8 ± 1.5. Twenty-seven patients (54 body areas) were considered as treatment "responders." In these individuals, mean skinfold thickness decreased from 35.4 ± 9.9 mm pretreatment to 22.2 ± 7.6 mm at 12 weeks (mean change: −40%; P < .001). Mean change in skinfold thickness was greater with ≥3 vs 1 to 2 cycles of CoolSculpting (P = .01). Patient satisfaction was high (n = 51/58; 88%). No adverse events were recorded. The study shows that multiple cycles/sessions of CoolSculpting can safely improve overall treatment benefit in body contouring, with greater decreases in skinfold thickness than have typically been previously observed.

Ultrasound assessment of abdominal adipose panniculus in patients treated with a single session of cryolipolysis in a clinical setting

“…Our results are in line with those published by McKeow & Payne, 22 who evaluated the effectiveness of cryolipolysis (multiple cycles/sessions) in 28 subjects with localized fat in at least one area of their body. They found a significant fat reduction, approximately 40%, in the different treated areas 22 . In favor to our study, it should be mentioned that they administered the CoolSculpting treatment over two sessions in some areas, although they did not find significant differences among patients who underwent one session and those who underwent two ones 22 …”

“…McKeow & Payne, 22 the mean reduction in localized abdominal fat seemed to be substantially greater than those reported in a systematic review of previous studies. 24 Hwang et al 25 assessed the effect of a single session of cryolipolysis on visceral and subcutaneous adipose tissue over a period of 12 weeks.…”

“…They found a significant fat reduction, approximately 40%, in the different treated areas. 22 In favor to our study, it should be mentioned that they administered the CoolSculpting treatment over two sessions in some areas, although they did not find significant differences among patients who underwent one session and those who underwent two ones. 22 It is not easy to compare our results with those reported by…”

“…Payne, 22 who evaluated the effectiveness of cryolipolysis (multiple cycles/sessions) in 28 subjects with localized fat in at least one area of their body. They found a significant fat reduction, approximately 40%, in the different treated areas.…”

“…McKeow & Payne, 22 since there were differences in treatment (they administered from 1 to 8 cycles in one or two sessions, while we administered 4-to-6 cycles in one session) and in the outcomes (they measured skinfold thickness, while we evaluated thickness reduction measured with ultrasounds and contour reduction).…”