Sildenafil citrate use in Addis Ababa: characteristics of users and pharmacists’ dispensing practices

Gebregeorgise, Dawit Teshome; Belay, Yajeb Melesse; Sporrong, Sofia Kälvemark

doi:10.1007/s11096-017-0558-8

Cited by 4 publications

(3 citation statements)

References 33 publications

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“…It is essential to have medical consultation to treat ED as several medical risk factors could cause the disorder as stated previously. Overall, three-fourths of sexenhancing medication users consumed them after friends' consultations or via announcements, and only 19.9% of users had appropriate medical session [23] . According to a cross-sectional survey conducted in Egypt, 58.35% of sexenhancing medicine users obtained them for recreational purposes and 15.6% of them used drugs to improve the time and frequency of intercourse.…”

Section: Resultsmentioning

confidence: 99%

Users under the influence of sex-enhancing medications: prevalence, demographics, and sexual features

Aboraia

Raheem²,

ELSAWAH³

et al. 2022

Human Andrology

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Background: Erectile dysfunction (ED) is considered the prime sexual dysfunction attracting public attention among men all over the world. It ranges from partial decrease in penile rigidity to a complete erectile failure. To overcome this issue, sexenhancing medications have become popular among men. Aim: The main objective of this work was to determine the prevalence, demographics, and sexual features of sex-enhancing medications users among Egyptians. Patients and Methods: A total of 1916 adult males were included in the present study. This cross-sectional study was conducted between August 2020 and July 2021. Participants were invited to fill a self-structured questionnaire through 'Google Forms.' The form included three main sections for sociodemographic data; sexual activity, and sex-enhancing medication history and brief sexual functioning inventory score analysis (BSFI). Results: Our finding showed that 48.4% of the subjects used sex-enhancement drugs. After completing the BSFI score variables, the results revealed that there was a highly statistically significant difference for the total BSFI score between sexenhancement drug users and nonusers (23.4±5.7 and 21.02±4.5, respectively), with less than 0.001. Regarding the drugs used, the majority (67.9%) used sildenafil. Strengths and limitations: In the Egyptian society, talking about sex problems concerns most males and they get ashamed when talking about it. Sex-enhancement drugs are being circulated in Egypt in a nonmedical way. Conclusion: Urban residency, marriage, high education, job, low-to-middle socioeconomic status, smoking, drinking alcohol, and having chronic hypertension and/or diabetes mellitus were identified as features of sex-enhancing pharmaceutical users, with impairment of sexual function among them.

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Section: Resultsmentioning

confidence: 99%

Users under the influence of sex-enhancing medications: prevalence, demographics, and sexual features

Aboraia

Raheem²,

ELSAWAH³

et al. 2022

Human Andrology

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“…The nonprescription availability of sildenafil and other PDE5Is could lead to inappropriate use, increased adverse effects, and an increased probability of addiction among users. A study conducted in Addis Ababa, Ethiopia [19] on pharmacist dispensing practices of PDE5Is claimed that most pharmacists knew that PDE5Is are prescription-only medicines but still dispensed them without prescriptions. The motive for this practice was pressure to maximize profit through increased sales of PDE5Is.…”

Section: Discussionmentioning

confidence: 99%

Utilization Trends of Phosphodiesterase Type-5 Inhibitors for Erectile Dysfunction Between 2019 and 2023 in Tanzania

Sangeda,

Kadinde,

Masatu

et al. 2024

Cureus

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IntroductionErectile dysfunction (ED) profoundly affects millions of people globally, including interfering with mental health and quality of life. Phosphodiesterase type-5 inhibitors (PDE5Is) such as sildenafil are pivotal in ED treatment. This study aimed to examine the utilization patterns of PDE5Is in Tanzania. Materials and methodsIn this retrospective longitudinal study, data on sildenafil and other similar PDE5Is imported between 2019 and 2023 were sourced from the Tanzania Medicines and Medical Devices Authority (TMDA). Pre-processing and visualization were performed using Microsoft Power BI Desktop, and further analysis was performed using IBM SPSS Statistics for Windows, Version 26 (Released 2019; IBM Corp., Armonk, New York, United States). Utilization trends were ascertained through curve fitting, Holt's linear trend model, and autoregressive integrated moving average (ARIMA) models. The defined daily doses (DDDS) per 1000 inhabitants (DID) were calculated using the World Health Organization (WHO) Anatomical Therapeutic Chemical (ATC) Classification System and the DDD methodology endorsed by the WHO Collaborating Centre for Drug Statistics Methodology. ResultsBetween 2019 and 2023, there was a pronounced increase in the importation of approximately 587 consignments of PDE5Is. Employing the Holt model (R-square = 0.843), a substantial increase from 0.220910 DID in 2019 to 0.534272 DID by 2025 was observed and anticipated. The period witnessed sildenafil dominating 75.5% of the total use, with Erecto being the most consumed brand (37.6% of total DID). Notably, 2022 had the highest surge (27.2% of the total), albeit a slight decline was observed in 2023 (20.5%). This trend was supported by a linear regression model (R-square = 0.889). ConclusionWe found increasing annual trends of PDE5Is of utilization. This requires critical oversight and effective policies to ensure appropriate use and risk minimization.

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“…In the Ethiopian context, due to the lack of strong regulations, sildenafil can be easily accessed from pharmacies without a prescription (1,(9)(10)(11). A qualitative study conducted in Addis Ababa, Ethiopia revealed that there was a widespread use of sildenafil citrate and the main reasons for the utilization were to gain sexual confidence and suppress anxieties associated with a feeling of loss of manhood (12).…”

Section: Introductionmentioning

confidence: 99%

The Weekend Drug; Recreational Use of Sildenafil Citrate and Concomitant Factors: A Cross-Sectional Study

et al. 2021

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Background: Men who use erectile dysfunction medications for recreational purposes may be at increased risk of becoming psychologically dependent, which in turn could lead to psychogenic-based erectile dysfunction symptoms. Sildenafil has become one of the most commonly prescribed and abused drugs available today.Objectives: This study aimed to describe the utilization pattern and associated factors of sildenafil citrate among its users visiting community pharmacies in Gondar, Ethiopia.Methods: A facility-based cross-sectional study was conducted from March 20, 2017 to May 10, 2017, among male clients who visited community pharmacies in Gondar town, North West Ethiopia. A self-administered, structured questionnaire was used to collect data from Sildenafil users older than 18 years, that started using the drug (Sildenafil) for at least 6 months before the data collection period. A regression analysis was conducted to determine the association between study variables, and a P-value of <0.05 was considered to declare statistical significance.Results: A total of 65 men participated in the study. Of the total study participants, 33.8% were aged 25–34 years and about 40% of them had multiple sexual partners. The use of sildenafil for recreational purposes was 66.2% and was found to be higher than its use for medical purposes 33.8%. Use of the drug for <1-year duration (AOR = 34.086, 95% CI [2.90, 401.37]) and 2 years duration (AOR = 21.42: 95% CI [2.10, 218.82]) were significantly associated with its use for recreational purpose. Non-recreational use of sildenafil includes erectile problems associated with diabetes mellitus (27.1%), heart disease (9.2%), hyperlipidemia (4.2%), and relationship problems due to stress and poor communication (3.1%).Conclusion: Most men who use sildenafil citrate do so for recreational purposes, and use of sildenafil citrate for 2 years or less was associated with recreational use. There should be a collaborative effort among pharmacists, health professionals, and policymakers to improve the rational use of sildenafil.

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Sildenafil citrate use in Addis Ababa: characteristics of users and pharmacists’ dispensing practices

Cited by 4 publications

References 33 publications

Users under the influence of sex-enhancing medications: prevalence, demographics, and sexual features

Users under the influence of sex-enhancing medications: prevalence, demographics, and sexual features

Utilization Trends of Phosphodiesterase Type-5 Inhibitors for Erectile Dysfunction Between 2019 and 2023 in Tanzania

The Weekend Drug; Recreational Use of Sildenafil Citrate and Concomitant Factors: A Cross-Sectional Study

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