Silent Neoplastic Cardiac Invasion in Small Cell Lung Cancer: A Case Report and Review of the Literature

Abstract

Patient: Female, 66Final Diagnosis: Small cell lung cancerSymptoms: Impaired memoryMedication: —Clinical Procedure: Chest X-ray • computed tomography • magnetic resonance imaging • electrocardiogramSpecialty: OncologyObjective:Rare co-existance of disease or pathologyBackground:Secondary malignant tumor of the heart is one of the most life-threatening complications of lung cancer. Several published case reports have documented non-small cell lung cancer (NSCLC) patients with neoplastic cardiac invasion. However, the number of reported cases of small cell lung cancer (SCLC) with neoplastic cardiac invasion is limited.Case Report:We present a rare case of advanced SCLC in a patient with asymptomatic neoplastic cardiac invasion. We also discuss radiation therapy modalities that should be considered in SCLC patients with cardiac invasion.Conclusions:Clinicians should be vigilant about cases of SCLC with asymptomatic intra-cardiac invasion and practice caution when diagnosing, as well as treating with radiation as a monotherapy.

An extensive surgical resection in stage T4 small cell lung cancer with cardiac invasion: A case report and literature review

“…After an extensive search, we discovered that none of the 7 precedents reported cases involving cardiac invasion of SCLC had surgical resection of the lung cancer ( Table 1 ) [ [8] , [9] , [10] , [11] , [12] , [13] , [14] ]. Most patients were not eligible for surgery because of poor health or the presence of multiple extrapulmonary metastases.…”

Dispne ile başvuran bir kronik obstruktif akciğer hastasında intrakardiyak kitleden tanı alan skuamoz hücreli karsinom olgusu

“…Several published case reports have documented non-small cell lung cancer (NSCLC) patients with neoplastic heart invasion. However, the number of small cell lung cancer (SCLC) cases with neoplastic cardiac invasion is limited 4 . In this article, we present our case of non-small cell lung cancer with cardiac invasion who presented to the emergency department with dyspnea.…”

Lung carcinoma extended to the left atrium through the right inferior pulmonary vein

“…The direct extension of left atrial tumor via pulmonary veins is uncommon ( 1 , 2 ). There are two types of cardiac invasion: direct invasion and expansion through a “limited” space (such as the pulmonary artery and vein) ( 3 ).…”