1995
DOI: 10.1515/jpme.1995.23.6.493
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“Silent” patent ductus arteriosus and bronchopulmonary dysplasia in low birth weight infants

Abstract: We conducted a clinical study on the antecedents of bronchopulmonary dysplasia (BPD) in 290 premature RDS infants with < or = 1.75 kg birth weight (BW). They were enrolled in a prospective trial of indomethacin treatment for "silent" patent ductus arteriosus (PDA), screened by 2-D echocardiographic and pulsed Doppler evaluation on the third day of life. The trial took place at the NICU of the Pediatric Department of Padua University between January 1987 and December 1991. Out of 290 infants screened, 96 had ev… Show more

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Cited by 7 publications
(1 citation statement)
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“…Surfactant, by assisting the natural postnatal fall in pulmonary artery pressure (PAP), has been shown to alter the timing of clinical presentation; specifically, by increasing the volume of the systemo‐pulmonary shunt which leads to an earlier clinical presentation 3031. The existence of a hemodynamically significant but ‘silent ductus’ has been confirmed by cardiac catherization 3233 and detailed echocardiographic evaluation 34.…”
Section: Introductionmentioning
confidence: 99%
“…Surfactant, by assisting the natural postnatal fall in pulmonary artery pressure (PAP), has been shown to alter the timing of clinical presentation; specifically, by increasing the volume of the systemo‐pulmonary shunt which leads to an earlier clinical presentation 3031. The existence of a hemodynamically significant but ‘silent ductus’ has been confirmed by cardiac catherization 3233 and detailed echocardiographic evaluation 34.…”
Section: Introductionmentioning
confidence: 99%