“Silent” subendocardial infarcts: fact or fiction?

The endocardial extent of reperfused first‐time myocardial infarction is more predictive of pathologic Q waves than is infarct transmurality: a magnetic resonance imaging study

“…Based on animal studies, Prinzmetal et al, (1954) stated that transmural MI was required for pathological Q waves to appear. More recently, however, histopathology (Pipberger & Lopez, 1980;Phibbs, 1983;Spodick, 1983) and imaging studies Moon et al, 2004;Engblom et al, 2005;Kaandorp et al, 2005) have shown that Q waves on ECG are not as closely related to transmural MI as previously reported.…”

“…, (1954) stated that transmural MI was required for pathological Q waves to appear. More recently, however, histopathology (Pipberger & Lopez, 1980; Phibbs, 1983; Spodick, 1983) and imaging studies (Wu et al. , 2001; Moon et al.…”

Size and transmural extent of first-time reperfused myocardial infarction assessed by cardiac magnetic resonance can be estimated by 12-lead electrocardiogram

“…However, more recent literature has rejected the notion that Q waves can be used to differentiate transmural from non-transmural MI (25)(26)(27). Furthermore, studies in patients with …”

The relationship between the electrocardiographically estimated infarct size and 1 ‐ and 2‐year survival in acute myocardial infarction

“…This classification has been criticized in recent years since autopsy studies have shown that the presence of Q waves on standard ECG is not equivalent to transmural MI and transmural MI can occur without the development of Q waves (Savage et al, 1977;Sullivan et al, 1978). It has therefore been proposed that this type of subdivision should not be made on the basis of ECG findings (Pipberger and Lopez, 1980). Several previous studies have compared the clinical course and prognosis during the in-hospital period between patients with Q waves and those without Q waves.…”