Silica-bonded N-propyl sulfamic acid as an efficient catalyst for the formylation and acetylation of alcohols and amines under heterogeneous conditions

Nano silica-bonded N-propylsulfamic acid as an efficient and environmentally benign catalyst for the synthesis of 1,5-benzodiazepines

“…Various chemical transformations reported with this catalyst include synthesis of aryl-14H-dibenzo[a,i]xanthenes, formylation and acetylation of alcohols and amines, synthesis of 1,8-dioxodecahydroacridines/1,8-dioxo-octahydroxanthenes/quinoxalines, chemoselective synthesis of 1,1-diacetates, transesterification of soybean oil/esterification of oleic acid with methanol, synthesis of 3,4-dihydropyrimidin-2-(1H)-ones/thiones [1][2][3][4][5][6], and so on. In recent years, growing attention has been devoted toward developing novel nanocatalysts [7,8].…”

Silica-Bonded N-Propyl Sulfamic Acid Catalyzed One-Pot Synthesis of Aryl-14-H-dibenzo[a,i]xanthenes

“…NMR spectra were determined on Bruker AV-400 instrument at room temperature using TMS as internal standard, coupling constants (J) were measured in Hz; IR spectra were determined on FTS-40 infrared spectrometer; Elemental analysis were performed by a Vario-III elemental analyzer; Mass spectra were taken on a Macro mass spectrometer (Waters) by electro-spray method (ESIMS); Melting points were determined on a XT-4 binocular microscope and were uncorrected; SBNPSA was prepared according to literature 10 ; Commercially available reagents were used throughout without further purification unless otherwise stated.…”

Synthesis of N-Formylation of Amines using Various Ion Exchanged Forms of Zeolite-A as Catalysts

“…The main application of Formamides is to use in the synthesis of Formamidines [7] and in peptide synthesis acts as useful amino protecting group [8]. Various methods have been previously reported in literature for the synthesis of N-Formylation of amines and various catalysts were used for this reaction, such as acetic formic anhydride [9], activated formic acid using Dicyclohexylcarbodiimide [10] or,1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide [11], chloral [12], activated formic esters [13], ammonium formate [14], 2,2,2-trifluoroethyl formate [15], ZnO [16], PEG-400 [17], Formic acid-ZnCl 2 [18], polyvinyl alcohol [19], Na + -montmorillonite [20], Nano Cerium Oxide [21], Natrolite zeolite [22], HCOOH Sodium formate [17], Silica-bonded N-Propyl Sulfamic acid [23], TiCl 3 (OTF) [24], CDMT [25], KF-AL 2 O 3 [26], Formic acid in Toluene [18], Formic acid in polyethylene glycol [17], Natural HEU Zeolite [27] . However above listed methods have some limitations such as long reaction time, formation of undesirable byproducts, hygroscopicity expensive reagents, and thermal instability of the reagents, and high temperature for reaction completion.…”