Silica Colloidal Membranes with Enantioselective Permeability

Leon, Patricia A. Ignacio-de; Abelow, Alexis E.; Cichelli, Julie; Zhukov, A. Yu.; Stoikov, Ivan I.; Zharov, Ilya

doi:10.1002/ijch.201400031

Cited by 8 publications

(10 citation statements)

References 49 publications

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“…Similar to the studies on charge-based selectivity, most of this work focused on opal layers covering electrodes as opposed to free-standing membranes. By attaching chiral selectors such as enantiopure molecules 277 or thiacalixarene moieties 278 and controlling solvent polarity, permeation selectivities that range between 2 and 4.5 can be achieved between optical isomers. 279 While grafting polymer brushes with chiral selector moieties (e.g., polypeptides) onto the silica spheres can increase the density of chiral binding sites within the pores, it would also narrow them down.…”

Section: Chemo-selective Membranes: Separation Of Organic Molecules B...mentioning

confidence: 99%

“…280 When thicker opal films were sintered to create free-standing membranes, lower enantioselectivity was observed due to the loss of functionalizable groups lining the pores. 278 Although films fabricated by self-assembled of silica More recently, graphene oxide (GO) has been used to create functionalizable membrane pores for enantioselective membranes. GO membranes can be effective molecular sieves with ultrafast water permeation.…”

Section: Chemo-selective Membranes: Separation Of Organic Molecules B...mentioning

confidence: 99%

“…Films with grafted chiral polymers exhibited comparable selectivities to those modified with a chiral selector molecule, possibly because most of the chiral sites on the grafted polymers were not accessible due to pore narrowing . When thicker opal films were sintered to create free-standing membranes, lower enantioselectivity was observed due to the loss of functionalizable groups lining the pores . Although films fabricated by self-assembled of silica offer high chiral selectivity, making them into membranes without damaging a high fraction of functional groups is still a challenge.…”

Section: Chemo-selective Membranes: Separation Of Organic Molecules B...mentioning

confidence: 99%

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Controlling and Expanding the Selectivity of Filtration Membranes

2018

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Chemical separations account for about 50% of costs and energy use associated with chemical and petrochemical manufacturing, corresponding to about 10% of all energy use in the U.S. Membrane separations are highly energy efficient, simple to operate, scalable, and portable. Broader use of membranes is limited by the selectivity of available membranes, mostly confined to the separation of species about an order of magnitude or more different in size in the liquid phase. This perspective focuses on new approaches for creating liquid filtration membranes that can perform more challenging separations. We first discuss the selectivity mechanisms of currently available membranes and compare them with the operation of biological systems that exhibit enhanced selectivity. Then, we review some approaches for creating isoporous membranes with narrow pore size distributions for enhanced size-based selectivity. We discuss biological systems that exhibit selectivity based on factors beyond size and how they can inspire the design of membranes capable of complex separations. After a review of approaches for creating membranes for separating similarly sized solutes, based on their charge, we discuss the development of membranes that can perform even more challenging separations, differentiating between solutes of similar size and charge based on other molecular criteria. This burgeoning area of research promises to transform chemical and pharmaceutical manufacturing if membranes with sufficient selectivity and permeability for realistic separations can be prepared using scalable manufacturing methods.

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Section: Chemo-selective Membranes: Separation Of Organic Molecules B...mentioning

confidence: 99%

Section: Chemo-selective Membranes: Separation Of Organic Molecules B...mentioning

confidence: 99%

Section: Chemo-selective Membranes: Separation Of Organic Molecules B...mentioning

confidence: 99%

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Controlling and Expanding the Selectivity of Filtration Membranes

2018

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“…light, electric field, magnetic field), and directed by linking surface functional groups. 25, 44–47 For the fabrication of nanofluidic crystal, researchers mainly adopt capillary force-assisted assembly of nanoparticles, which can be categorized into two methods: vertical deposition 29, 48–59 and horizontal deposition. 60–64 Figure 6(a) shows the scheme of vertical deposition.…”

Section: Fabrication Of Nanofluidic Crystalmentioning

confidence: 99%

“…58 The same group further realized enantiomers separation in nanofluidic crystal modified with chiral selector moieties, achieving performance on par with most reported polymer-based solid membranes and bulk liquid membranes. 59 Wirth and co-workers 29 demonstrated high-speed chemical separations in a 200 nm nanofluidic crystal. Three cationic, hydrophobic dyes were separated based on reversed-phase adsorptivity in 6 s over an unprecedentedly short separation length of 1 mm by using a C 18 stationary phase and a field strength of 1000 V/cm (Figure 10(a)).…”

Section: Applicationsmentioning

confidence: 99%

Nanofluidic crystals: nanofluidics in a close-packed nanoparticle array

2017

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With various promising applications demonstrated, nanofluidics has been of broad research interest in the past decade. As nanofluidics matures from proof of concept towards practical applications, it faces two major barriers: expensive nanofabrication and ultra-low throughput. Up to date, the only material that enables nanofabrication-free, high-throughput, yet precisely controllable nanofluidic systems is the close-packed nanoparticle array, i.e. nanofluidic crystal. Recently, significant progresses in nanofluidics have been made using nanofluidic crystal, including high-current ionic diodes, high-power energy harvesters, efficient biomolecular separation, and facile biosensors. Nanofluidic crystal is seen as a key to applying nanofluidic concepts into real–world applications. In this review, we introduce the key concepts and models in nanofluidic crystal, summarize the fabrication methods, and discuss in-depth the various applications of nanofluidic crystal, highlighting its advantages in simple fabrication, low cost, flexibility, and high throughput. Finally, we provide our prospects on the future of nanofluidic crystal and its potential impacts.

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