Silicon content of bone callus in experimental fractures

Belous, A. M.; Skoblin, A. P.

doi:10.1007/bf00786743

Cited by 1 publication

(2 citation statements)

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“…Larger scale trials or intentional induction of lameness in future studies will be necessary to determine if the novel silicon supplement alleviates lameness in poultry. This type of study would also allow further investigation into the potential mechanisms behind the role of silicon in bone and tissue development and repair that have been previously outlined in rabbits 5 , poultry 3 and in humans 32 .…”

Section: Discussionmentioning

confidence: 95%

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Bioavailability of a novel form of silicon supplement

Scholey

Belton

Burton

et al. 2018

Sci Rep

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In this study, we assessed uptake and potential efficacy of a novel, pH neutral form of silicon supplement in vitro and using broiler chickens as a model species. In vitro bioavailability of this supplement was significantly higher than other commercial supplements tested, all of which claim available silica content. To confirm bioavailability of the new supplement in vivo, a broiler chick feeding trial reported blood uptake that was significantly higher than a Bamboo-derived silicon supplement. We assessed dose response of the novel supplement in a further study with increased dose related levels of silicon being detected in the blood and tibia. We found tibia and foot ash residue as a percentage of dry mass was higher with inclusion of the novel supplement in the diet, particularly in young birds and that this was followed by significant increase in tibia breaking strength. This novel supplement may therefore have applications in the improvement of bone integrity, with implications for the reduction of lameness in broilers. These results indicate the novel silica supplement is readily absorbed in chicks, and transported in the blood supply to sites such as the skeleton due to it being present in a non-condensed, monomeric form. There is potential for wider application of this silica supplement in other species where bone breakages are a problem, including high performance sport.

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Section: Discussionmentioning

confidence: 95%

“…However, these early poultry studies were on a genetically different bird to today’s broilers. Silicon also appears to have a role in the early stages of bone regeneration following trauma 5 , but this is not yet fully understood.…”

Section: Introductionmentioning

confidence: 99%