2016
DOI: 10.1063/1.4962294
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Silk patterns made by direct femtosecond laser writing

Abstract: Silk patterns in a film of amorphous water-soluble fibroin are created by tailored exposure to femtosecond-laser pulses (1030 nm/230 fs) without the use of photoinitiators. This shows that amorphous silk can be used as a negative tone photoresist. It is also shown that water insoluble crystalline silk films can be precisely ablated from a glass substrate achieving the patterns of crystalline silk gratings on a glass substrate. Bio-compatible/degradable silk can be laser structured to achieve conformational tra… Show more

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Cited by 26 publications
(29 citation statements)
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“…For instance, laser induced forward transfer (LIFT) [34] could be used to directly and selectively seed scaffolds with cells [9]. The 3D femtosecond laser nanolithography could make sub-micrometer additions to the macro-structure of produced scaffolds [31], out of huge variety of different materials, including non-photosensitized [35,36] or fuctionalized [37] polymers. In essence, pairing of various processing techniques is a powerful way to offset most of the technological drawbacks and accentuate advantages [1,33].…”
Section: Discussionmentioning
confidence: 99%
“…For instance, laser induced forward transfer (LIFT) [34] could be used to directly and selectively seed scaffolds with cells [9]. The 3D femtosecond laser nanolithography could make sub-micrometer additions to the macro-structure of produced scaffolds [31], out of huge variety of different materials, including non-photosensitized [35,36] or fuctionalized [37] polymers. In essence, pairing of various processing techniques is a powerful way to offset most of the technological drawbacks and accentuate advantages [1,33].…”
Section: Discussionmentioning
confidence: 99%
“…For instance, laser induced forward transfer (LIFT) [26] could be used to directly and selectively seed scaffolds with cells [9]. 3D femtosecond laser nanolithography could make sub-micrometer additions to the macro-structure of produced scaffolds [23], out of huge variety of different materials, including non-photosensitized [27,28] or fuctionalized [29] polymers. In essence, pairing of various processing techniques is a powerful way to offset most of the technological drawbacks and accentuate advantages [1,25].…”
Section: Discussionmentioning
confidence: 99%
“…The fact that material can be structured without photoinitiator with a fabrication window comparable to that of photosensitized material is a promising discovery for other science fields as well. Earlier studies dedicated to pure material structuring by femtosecond laser pulses [16,45] have shown to be complicated and slow. If such pure material can be structured at a relatively high speed (∼mm/s) it would become suitable for biomedical applications, where structure dimensions are in the range of mm-cm [46].…”
Section: Discussionmentioning
confidence: 99%