2022
DOI: 10.1021/acsami.2c03922
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Siloxane Hybrid Material-Encapsulated Highly Robust Flexible μLEDs for Biocompatible Lighting Applications

Abstract: Flexible micro-light-emitting diodes (f-μLEDs) have been regarded as an attractive light source for the next-generation human–machine interfaces, thanks to their noticeable optoelectronic performances. However, when it comes to their practical utilizations fulfilling industrial standards, there have been unsolved reliability and durability issues of the f-μLEDs, despite previous developments in the high-performance f-μLEDs for various applications. Herein, highly robust flexible μLEDs (f-HμLEDs) with 20 × 20 a… Show more

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Cited by 14 publications
(13 citation statements)
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“…For proceeding the LIVE/DEAD assay, N2a cells were subcultured in a cell culture dish (growth area: 9.24 cm 2 ) at a density of 200,000 cells per well and incubated for 24 h. Then 500 μL of MOFC solution with a concentration of 0.250 mg mL –1 was injected into the cell culture dish. N2a cells were further incubated for 7 days in the growth medium containing MOFC nanoparticles and stained by LIVE/DEAD assay kit consisting of calcein AM and ethidium homodimer-1 as referred to in the literature. , The LIVE/DEAD assay results were obtained by a fluorescence microscope (Eclipse 80i, Nikon Inc., Japan). MTS assay is a colorimetric method that determines live cells by measuring the absorbance of 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2 H -tetrazolium reagent.…”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…For proceeding the LIVE/DEAD assay, N2a cells were subcultured in a cell culture dish (growth area: 9.24 cm 2 ) at a density of 200,000 cells per well and incubated for 24 h. Then 500 μL of MOFC solution with a concentration of 0.250 mg mL –1 was injected into the cell culture dish. N2a cells were further incubated for 7 days in the growth medium containing MOFC nanoparticles and stained by LIVE/DEAD assay kit consisting of calcein AM and ethidium homodimer-1 as referred to in the literature. , The LIVE/DEAD assay results were obtained by a fluorescence microscope (Eclipse 80i, Nikon Inc., Japan). MTS assay is a colorimetric method that determines live cells by measuring the absorbance of 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2 H -tetrazolium reagent.…”
Section: Methodsmentioning
confidence: 99%
“…N2a cells were further incubated for 7 days in the growth medium containing MOFC nanoparticles and stained by LIVE/DEAD assay kit consisting of calcein AM and ethidium homodimer-1 as referred to in the literature. 65,66 The LIVE/DEAD assay results were obtained by a fluorescence microscope (Eclipse 80i, Nikon Inc., Japan). MTS assay is a colorimetric method that determines live cells by measuring the absorbance of 3-(4,5dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium reagent.…”
Section: Methodsmentioning
confidence: 99%
“…For LIVE/DEAD staining assay, N2a cells were spread at a density of 5000 cells dish –1 in a confocal dish (diameter: 20 mm), and 100 μL of linnaeite nanoparticle solution (0.025 mg mL –1 in DMEM) was injected to the cell culture dish after 24 h of incubation. A LIVE/DEAD staining assay was performed at day 1 and 3 after the nanoparticle injection, as done in a previous study , For the alamarBlue assay, N2a cells were spread at a density of 5,000 cells well –1 in a 96-well plate, and incubated with different concentrations of linnaeite nanoparticles (0 to 500 μg mL –1 ) for a day after allowing the cell adhesion for 24 h. To confirm the alleviation effect of linnaeite nanoparticles on βPFOs, we incubated N2a cells in a 96-well plate for 48 h with a low-serum medium (DMEM containing 0.1% FBS and 1% AA) following the literature with modifications. Afterward, the N2a cells were treated by 1.5 uL of βPFO solution (90 μM) for 72 h, and the cell viability was assessed by an alamarBlue assay through a microplate reader (Victor 3, PerkinElmer Inc., USA) that equipped with optimal excitation and emission filters (λ ex = 560 nm, λ ex = 590 nm).…”
Section: Methodsmentioning
confidence: 99%
“…The chemistry of the Si-O-Si bond was already illustrated in Section 3.1 ( Figure 8 ), and here will be described the capacity of siloxanes to act as a collective encapsulating agent with high chemical thermal and mechanical stability, as recently presented by Bae’s group for the stabilization of scQDs in different conditions [ 83 , 84 , 85 , 86 , 87 ].…”
Section: Stabilization Of the Qds At A Single And Collective Levelmentioning
confidence: 96%