Silver‐Catalyzed Carbofluorination of Olefins and α‐Fluoroolefins with Carbamoyl Radicals

Abstract

The reactivity of carbamoyl radicals, generated in situ from sodium oxamate salts, has been investigated in the context of radical carbofluorination reactions of olefins and a‐fluoroolefins, respectively. Both transformations are catalyzed by silver salts and required the presence of potassium persulfate (K2S2O8) and SelectfluorTM as a radicophilic fluorine source. The reported methods provide a direct access to beta‐fluoroamides and beta,beta‐difluoroamides.