Silver-catalyzed radical reaction of 2H-indazoles with 1,3-dicarbonyl compounds to access 3-dicarbonyl indazoles

Recent advances in C–H functionalization of 2H-indazoles

“…In 2021, Li reported a silver-catalyzed radical oxidative coupling of 2 H -indazoles with 1,3-dicarbonyl compounds to access 3-dicarbonyl indazoles (Scheme 19). 40 The reactions were carried out in the presence of AgNO 3 as the catalyst and Na 2 S 2 O 8 as the oxidant. A series of 1,3-dicarbonyl-2 H -indazole products were obtained in yields of up to 82%.…”