Silver-doped metal layers for medical applications

Abstract

Biological, physical and mechanical properties of silver-doped layers of titanium alloy Ti6Al4V and 316 L steel prepared by pulsed laser deposition were studied. Metallic silverdoped coatings could be a new route for antibacterial protection in medicine. Thin films of silver and silver-doped materials were synthesized using KrF excimer laser deposition. The materials were ablated from two targets, which were composed either from titanium alloy with silver segments or from steel with silver segments. The concentration of silver ranged from 1.54 to 4.32 at% for steel and from 3.04 to 13.05 at% for titanium alloy. The layer properties such as silver content, structure, adhesion, surface wettability, and antibacterial efficiency (evaluated by Escherichia coli and Bacillus subtilis bacteria) were measured. Film adhesion was studied using a scratch test. The antibacterial efficiency changed with silver doping up to 99.9 %. Our investigation was focused on the minimum Ag concentration needed to reach high antibacterial efficiency, high film adhesion, and hardness.

Electrochemical detection of aqueous Ag+ based on Ag+-assisted ligation reaction

“…In recent decades, high toxic heavy metal ions, including silver, mercury and lead ions, have brought serious environment and health problems 1 2 3 . Silver, a widely used element in photographic, medical and electronic industry, is one of the most hazardous metal pollutions 4 5 6 . Nowadays, large amount of silver waste have been released directly into the environment every year, which may lead to the pollution of ambient water, soil and even food.…”

Oligonucleotide-Based Reusable Electrochemical Silver(I) Sensor and Its Optimization via Probe Packing Density

“…The development of simple, reliable, and practical sensors for the determination of environmental pollutants is a subject of considerable research. Of particular interest is the detection of silver, a hazardous pollutant that has been widely used in the medical, photographic, pharmaceutical, and electrical industries. − It has been reported that large quantities of silver are released directly into the environment every year, which may lead to the pollution of ambient water, soil, and even food. , The U.S. Environmental Protection Agency has declared that Ag + concentrations higher than 1.5 nM are toxic to fish and microorganisms, and the maximum contamination level for Ag + in drinking water has been set at 900 nM . Ag + can interact with various metabolites and sulfhydryl enzymes, leading to disorders such as stomach distress, skin irritation, nervous system damage, and organ edema. , Because of its adverse effects on human health, methods for the detection and quantification of Ag + are in high demand.…”