Silver-doped nanocomposite carbon coatings (Ag-DLC) for biomedical applications – Physiochemical and biological evaluation

Bociaga, Dorota; Komorowski, Piotr; Batory, D.; Szymański, W.; Olejnik, Alicja K.; Jastrzębski, K.; Jakubowski, Witold

doi:10.1016/j.apsusc.2015.07.117

Cited by 75 publications

(37 citation statements)

References 61 publications

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“…The high incidence of infections caused by the use of metallic biomedical implants and devices, including bone fracture fixation pins and hip and knee replacement, has a severe impact on human health and health care costs (Bociaga et al 2015;Percival et al 2015;Ceroni et al 2016;Dunne et al 2017). Prevention of bacterial adhesion on the surfaces of medical devices will have a major impact in preventing medical device-related infections.…”

Section: Introductionmentioning

confidence: 99%

Reduction of bacterial adhesion on titanium-doped diamond-like carbon coatings

Zhao

et al. 2018

Biofouling

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A range of titanium doped diamond-like carbon (Ti-DLC) coatings with different Ti contents were prepared on stainless steel substrates using a plasma-enhanced chemical vapour deposition technique. It was found that both the electron donor surface energy and the surface roughness of the Ti-DLC coatings increased with increasing Ti contents in the coatings. Bacterial adhesion to the coatings was evaluated against Escherichia coli WT F1693 and Pseudomonas aeruginosa ATCC 33347. The experimental data showed that bacterial adhesion decreased with the increases of the Ti content, the electron donor surface energy and surface roughness of the coatings, while the bacterial removal percentage increased with the increases of these parameters. The Ti-DLC coatings reduced bacterial attachment by up to 75% and increased bacterial detachment from 15 to 45%, compared with stainless steel control.

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Section: Introductionmentioning

confidence: 99%

Reduction of bacterial adhesion on titanium-doped diamond-like carbon coatings

Zhao

et al. 2018

Biofouling

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“…This lead to more complete and homogeneous endothelialization without triggering thrombotic clots. Antibacterial effects of DLC and doped DLC have been documented in [83]. Several reviews analyze DLC coatings and coating strategies.…”

Section: Diamond-like Carbon (Dlc) Coatingsmentioning

confidence: 99%

Recent Advances in Manufacturing Innovative Stents

et al. 2020

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Cardiovascular diseases are the most distributed cause of death worldwide. Stenting of arteries as a percutaneous transluminal angioplasty procedure became a promising minimally invasive therapy based on re-opening narrowed arteries by stent insertion. In order to improve and optimize this method, many research groups are focusing on designing new or improving existent stents. Since the beginning of the stent development in 1986, starting with bare-metal stents (BMS), these devices have been continuously enhanced by applying new materials, developing stent coatings based on inorganic and organic compounds including drugs, nanoparticles or biological components such as genes and cells, as well as adapting stent designs with different fabrication technologies. Drug eluting stents (DES) have been developed to overcome the main shortcomings of BMS or coated stents. Coatings are mainly applied to control biocompatibility, degradation rate, protein adsorption, and allow adequate endothelialization in order to ensure better clinical outcome of BMS, reducing restenosis and thrombosis. As coating materials (i) organic polymers: polyurethanes, poly(ε-caprolactone), styrene-b-isobutylene-b-styrene, polyhydroxybutyrates, poly(lactide-co-glycolide), and phosphoryl choline; (ii) biological components: vascular endothelial growth factor (VEGF) and anti-CD34 antibody and (iii) inorganic coatings: noble metals, wide class of oxides, nitrides, silicide and carbide, hydroxyapatite, diamond-like carbon, and others are used. DES were developed to reduce the tissue hyperplasia and in-stent restenosis utilizing antiproliferative substances like paclitaxel, limus (siro-, zotaro-, evero-, bio-, amphi-, tacro-limus), ABT-578, tyrphostin AGL-2043, genes, etc. The innovative solutions aim at overcoming the main limitations of the stent technology, such as in-stent restenosis and stent thrombosis, while maintaining the prime requirements on biocompatibility, biodegradability, and mechanical behavior. This paper provides an overview of the existing stent types, their functionality, materials, and manufacturing conditions demonstrating the still huge potential for the development of promising stent solutions.

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“…In the twenty-first century, most research pertains to the technology of DLC coatings, including the modification of these other atoms (in medical applications N, Si, Ti, O, F, and Ag) [22][23][24][25][26][27][28][29][30]. For their synthesis, the most common method is chemical vapor deposition.…”

Section: Pa Cvd and Dlc Layersmentioning

confidence: 99%

DLC Layers Created Using CVD Techniques and Their Application

Januś¹

2019

Chemical Vapor Deposition for Nanotechnology

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One way to obtain new materials with different properties is to modify existing ones to improve their inadequate properties. Due to the fact that many useful properties of materials, including resistance to wear and corrosion, coefficient of friction and biocompatibility, depend on the state of the surface, modern methods of surface engineering are particularly useful. They include the deposition of layers with a matching chemical composition and structure. In terms of applications, the most suitable seem to be amorphous or nanocrystalline layers containing carbon, nitrogen, silicon and hydrogen. They combine the advantageous properties of silicon carbide SiC and silicon nitride Si 3 N 4 and thus have a strong resistance to oxidation at high temperatures, high modulus of elasticity, low coefficient of friction and wear resistance. However, the silicon carbonitride compound is not thermodynamically stable under normal conditions and therefore must be obtained as a result of unconventional synthesis. One of these methods is chemical vapor deposition (CVD), including the most widely used plasma-assisted chemical vapor deposition (PACVD) techniques. The materials obtained, thanks to these techniques, have found and are still finding wider and wider application in many branches of industry and medicine.

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Silver-doped nanocomposite carbon coatings (Ag-DLC) for biomedical applications – Physiochemical and biological evaluation

Cited by 75 publications

References 61 publications

Reduction of bacterial adhesion on titanium-doped diamond-like carbon coatings

Reduction of bacterial adhesion on titanium-doped diamond-like carbon coatings

Recent Advances in Manufacturing Innovative Stents

DLC Layers Created Using CVD Techniques and Their Application

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