Silver Nanoparticles as Potential Antibiofilm Agents against Human Pathogenic Bacteria

Kyaw, Kaung; Harada, Ayaka; Ichimaru, Hiroaki; Kawagoe, Takayuki; Yahiro, Kinnosuke; Morimura, Shigeru; Ono, Koji; Tsutsuki, Hiroyasu; Sawa, Tomohiro; Niidome, Takuro

doi:10.1246/cl.161198

Cited by 12 publications

(3 citation statements)

References 18 publications

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“…Furthermore, we endorse the genius of traditional indigenous medicinal knowledge of the use of this particular silver rice in the treatment of GI infections. Because silver ions are known to be detrimental to pathogenic microbes, 24 the Ag-fortified rice is likely to be a potent curative of GI microbial infections. Garibsal rice is the only cereal to contain silver in its grains at concentrations greater than 10 mg/kg.…”

Section: ■ Conclusionmentioning

confidence: 99%

Unusual Accumulation of Silver in the Aleurone Layer of an Indian Rice (Oryza sativa) Landrace and Sustainable Extraction of the Metal

Gupta

Baksi

Roy

et al. 2017

ACS Sustainable Chem. Eng.

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Uptake of noble metals by cereal plants is not reported in literature. Our study of 505 native rice landraces showed that nine of them accumulate silver at a high concentration when grown in the same soil. Among these, a medicinal rice landrace from West Bengal, Garib-sal was found to accumulate silver at an especially high concentration in the grains. Cultivation of Garib-sal rice in three successive years in Basudha farm in the rice growing period of June–October confirmed that for the same concentration of silver in the soil (∼0.15 mg/kg), Garib-sal accumulates it in the grains to the extent of ∼15 mg/kg. Laboratory experiments also demonstrated that silver uptake by Garib-sal is significantly greater than for other varieties grown on the same soil, and that the metal accumulates mostly in the grain. To detect the location of deposition of silver in the grains, secondary ion mass spectrometry was performed. The images reveal that the silver is concentrated in the aleuronic layer of the rice bran. Its concentration decreases in the subaleurone and becomes negligible in the endosperm. Accumulation of silver does not alter the grain morphology and chemical characteristics. The metal may be extracted from the bran after milling of the rice, thereby causing no loss of the foodstuff.

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Section: ■ Conclusionmentioning

confidence: 99%

Unusual Accumulation of Silver in the Aleurone Layer of an Indian Rice (Oryza sativa) Landrace and Sustainable Extraction of the Metal

Gupta

Baksi

Roy

et al. 2017

ACS Sustainable Chem. Eng.

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“…In addition, nanoparticles kill bacteria by adsorbing on bacterial membranes and damaging the membrane structure . Silver nanoparticles also prevent biofilm formation by pathogenic bacteria . Despite these properties, the use of silver nanoparticles as antibacterial agents against infectious diseases is not common because silver nanoparticles are unstable and tend to form aggregates under physiological conditions in electrolytes such as inorganic salts and proteins.…”

Section: Introductionmentioning

confidence: 99%

“…16 Silver nanoparticles also prevent biofilm formation by pathogenic bacteria. 17 Despite these properties, the use of silver nanoparticles as antibacterial agents against infectious diseases is not common because silver nanoparticles are unstable and tend to form aggregates under physiological conditions in electrolytes such as inorganic salts and proteins. Aggregate formation decreases the release of silver ions from the nanoparticles, and reduces antibacterial activity at the site of infection.…”

Section: ■ Introductionmentioning

confidence: 99%

Gold Coating of Silver Nanoplates for Enhanced Dispersion Stability and Efficient Antimicrobial Activity against Intracellular Bacteria

et al. 2018

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Silver nanoparticles have antibacterial activity. However, the nanoparticles are unstable and easily form aggregates, which decreases their antibacterial activity. To improve the dispersion stability of silver nanoparticles in aqueous media and to increase their effectiveness as antibacterial agents, we coated triangular plate-like silver nanoparticles (silver nanoplates, Ag NPLs) with one or two layers of gold atoms (Ag@Au1L NPLs and Ag@Au2L NPLs, respectively). These gold coatings improved the dispersion stability in aqueous media with high salt concentrations. Ag@Au1L NPLs showed stronger antibacterial activity on pathogenic bacteria than Ag NPLs and Ag@Au2L NPLs. Furthermore, the Ag@Au1L NPLs decreased the number of bacteria in RAW 264.7 cells. The Ag@Au1L NPLs displayed no cytotoxicity towards RAW 264.7 cells and could be used as antibacterial agents for intracellular bacterial infections.

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Functionalized Antibacterial Nanoparticles for Controlling Biofilm and Intracellular Infections

Viswanathan

Rangasamy

Biswas

2019

Surface Modification of Nanoparticles for Targeted Drug Delivery

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Silver Nanoparticles as Potential Antibiofilm Agents against Human Pathogenic Bacteria

Cited by 12 publications

References 18 publications

Unusual Accumulation of Silver in the Aleurone Layer of an Indian Rice (Oryza sativa) Landrace and Sustainable Extraction of the Metal

Unusual Accumulation of Silver in the Aleurone Layer of an Indian Rice (Oryza sativa) Landrace and Sustainable Extraction of the Metal

Gold Coating of Silver Nanoplates for Enhanced Dispersion Stability and Efficient Antimicrobial Activity against Intracellular Bacteria

Functionalized Antibacterial Nanoparticles for Controlling Biofilm and Intracellular Infections

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