Silver nanoparticles fabricated by tannic acid for their antimicrobial and anticancerous activity

Fabrication of α-Fe2O3 Nanostructures: Synthesis, Characterization, and Their Promising Application in the Treatment of Carcinoma A549 Lung Cancer Cells

“…Dulbecco’s modified Eagle medium (DMEM) supplemented with 2 mM l -glutamine and 10% (v/v) fetal bovine serum (FBS) was used as a culture medium. 23 Phosphate-buffered saline (PBS; 0.01 M) was used to rinse the cultured cells, and then the cells were treated with a solution of TRY-EDTA followed by DMEM for resuspension. Later on, the A549 cells were treated with α-Fe 2 O 3 NPs at a concentration range of 15–60 μg/mL.…”

“…The cells were seeded in a CO 2 atmosphere incubated at 37 °C and a humidified atmosphere of 5% (v/v) CO 2 for a day until 80% confluency was reached. Dulbecco’s modified Eagle medium (DMEM) supplemented with 2 mM l -glutamine and 10% (v/v) fetal bovine serum (FBS) was used as a culture medium . Phosphate-buffered saline (PBS; 0.01 M) was used to rinse the cultured cells, and then the cells were treated with a solution of TRY-EDTA followed by DMEM for resuspension.…”

“… 14 The use of iron nanoparticles in the biomedical field has led to significant advantages in terms of diagnosis, 15 − 20 biomedical detection, 21 , 22 therapy, 17 and drug delivery. 14 , 23 The surface morphology and particle size of iron/iron oxide NPs could easily be controlled by a suitable synthetic method, which provides a specific application. 15 There are a few reports in the literature on the synthesis of iron oxide NPs, with limited applications because of large agglomeration and difficulty with dispersion in an aqueous medium, which prohibits in vitro application.…”

“…It is mostly synthesized by using the soft-templating method because of the easy approach with a low molecular weight polymer like polyethylene glycol (PEG) as a surfactant. , Many researchers have employed iron oxide nanoparticles thoroughly because of their unique properties such as low Curie temperature, high magnetic susceptibility, high surface area-to-volume ratio, high surface energy, tunable pore size, and uniform distribution, which provide a high demand for in vivo and in vitro application in the field of biomedical science to targeted drug delivery, magnetic resonance imaging (MRI), cancer hyperthermia, catalysis, biosensing, environmental remediations, and other industrial applications . The use of iron nanoparticles in the biomedical field has led to significant advantages in terms of diagnosis, − biomedical detection, , therapy, and drug delivery. , The surface morphology and particle size of iron/iron oxide NPs could easily be controlled by a suitable synthetic method, which provides a specific application . There are a few reports in the literature on the synthesis of iron oxide NPs, with limited applications because of large agglomeration and difficulty with dispersion in an aqueous medium, which prohibits in vitro application. , On the other hand, polymer-coated iron oxide NPs have gained much attention due to the balancing of magnetic and Van der Waals forces .…”

“…These have been investigated to produce more stable, soluble, biocompatible, and size-controlled NPs with desired shapes such as spherical, nanoflowers, nanotubes, and nanowires. Several chemical routes such as sol–gel, − co-precipitations, hydrothermal, sonochemical, microwave-assisted, physical routes as spray pyrolysis, chemical reduction, ,− thermal decompositions, and green synthesis as a biological route were used for the synthesis of metal NPs. Many researchers have successfully synthesized iron-based NPs for their application in in vitro and in vivo analysis − and obtained good results, i.e.…”