Silver nanoparticles in aquatic environments: Physiochemical behavior and antimicrobial mechanisms

Zhang, Chiqian; Hu, Zhiqiang; Deng, Baolin

doi:10.1016/j.watres.2015.10.025

Cited by 279 publications

(136 citation statements)

References 437 publications

(498 reference statements)

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“…Doctors are beginning to use them in wound dressings as anti-microbial agents, in topically applied creams used to prevent wound infections, and even finds success in use as anticancer applications [16][17][18][19][20].…”

Section: Silver Nano Particles (Snps)mentioning

confidence: 99%

A review on preparation methods of SNPs and their biomedical applications

Ut¹,

Mk²,

Gvsn³

2017

Front Nanosci Nanotech

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Researchers have identified Silver Nano Particles (SNPs) as a key area of interest because of their unique shape and size dependent biomedical properties. They have discovered and invented a variety of methods for the synthesis of SNPs such as microwave irradiation techniques, laser ablation synthesis, biological synthesis, photochemical synthesis and chemical synthesis etc. In this review paper we overview the preparation of SNPs through various synthesis methods and also their applications in the bio-medical field. The main aim of this paper is to keep up to date with the myriad ongoing synthesis methods of synthesis of NPs and also examine their applications especially in the field of medicine. Silver Nano Particles (SNPs)Silver (Ag) is a white colored, lustrous looking, physically soft, transition element metal having high thermal and electrical conductivity. It has been used by humans earlier than the recorded history due to its ornamental, medical and therapeutic benefits even before realizing that microbes are the causative agents of infections. It is used by people in many forms such as solutions, foils, coins, vessels, sutures, and in colloids such as lotions, ointments etc. It is one of the most prominent therapeutic elemental agent in medicine for surgical infections and infectious diseases. The tangible advantages of silver have a bigger weightage than the intangible risk factors [1].Nanoscience is a novel multidisciplinary subject that depends on the basic physical and chemical properties displayed by nano level objects [2,3]. Nanoparticles have been shown to display amazing electromagnetic, surface optical and chemically catalytic characteristics than the macro bulk material owing to their extremely low volume to surface area ratio [4,5]. Metal nanoparticles such as silver show different colors due to their Surface Plasmon Resonance (SPR) phenomenon. It is a group oscillatory behavior of the free electrons of the metal nanoparticles having the same frequency of the light wave interactions, resulting in resonance, causing the SPR band to form in the infrared and visible region [6]. Nanoparticles, especially the metallic ones, whose production can be done through various methods, the usual ones being physical and chemical methods. The above-mentioned methods produce high purity, well-defined nanoparticles, but the reagents used in the synthesis are hazardous, energy consuming, expensive, toxic and not suitable for physiological or ecological applications. Research regarding the synthesis of metal nanoparticles was extensively covered in the past three decades, but research of nanosynthesis , based on plant extracts, bloomed only in the last ten years [7][8][9][10][11][12][13].Silver nanoparticles are finding themselves in the limelight due to their biological, chemical and physical properties that contributes to the bactericidal and fungicidal effects, catalytic activity and finds applications in nanobiotechnological research [14,15]. Doctors are beginning to use them in wound dressings as an...

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Section: Silver Nano Particles (Snps)mentioning

confidence: 99%

A review on preparation methods of SNPs and their biomedical applications

Ut¹,

Mk²,

Gvsn³

2017

Front Nanosci Nanotech

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“…AgNP have an enormous potential to improve current technologies in multiple areas, from medicine and pharmacology to consumer products and bioremediation (Zhang, Hu, and Deng 2016), but not without the release of nanowastes into the natural environment (Cleveland et al 2012;Furman, Usenko, and Lau 2013). The estimated concentration of AgNP in surface waters, a potential human exposure route, is 0.088-10,000 ng/L.…”

Section: Introductionmentioning

confidence: 99%

Co-exposure to silver nanoparticles and cadmium induce metabolic adaptation in HepG2 cells

et al. 2018

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(2018) Co-exposure to silver nanoparticles and cadmium induce metabolic adaptation in HepG2 cells, Nanotoxicology, 12:7, 781-795, DOI: 10.1080/17435390.2018 Although multiple studies have reported the toxicological effects and underlying mechanisms of toxicity of silver nanoparticles (AgNP) in a variety of organisms, the interactions of AgNP with environmental contaminants such as cadmium are poorly understood. We used biochemical assays and mass spectrometry-based proteomics to assess the cellular and molecular effects induced by a co-exposure of HepG2 cells to AgNP and cadmium. Cell viability and energy homeostasis were slightly affected after a 4-h exposure to AgNP, cadmium, or a combination of the two; these endpoints were substantially altered after a 24-h co-exposure to AgNP and cadmium, while exposure to one of the two contaminants led only to minor changes. Proteomics analysis followed the same trend: while a 4-h exposure induced minor protein deregulation, a 24-h exposure to a combination of AgNP and cadmium deregulated 43% of the proteome. The toxicity induced by a combined exposure to AgNP and cadmium involved (1) inactivation of Nrf2, resulting in downregulation of antioxidant defense and proteasome-related proteins, (2) metabolic adaptation and ADP/ATP imbalance, and (3) increased protein synthesis possibly to reestablish homeostasis. The adaptation strategy was not sufficient to restore ADP/ATP homeostasis and to avoid cell death. ARTICLE HISTORY

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“…A major role in the antibacterial properties of AgNPs is played by the release of Ag + ions from their surface . To understand and predict how AgNPs behave in various environments, it is essential considering the thermodynamics driving the dissolution of the material and how this phenomenon is related to the physicochemical properties of the particles and environmental conditions . Several factors such as composition of the dispersion medium, pH and oxidation state of Ag in the AgNPs have been shown to alter the properties and dissolution rates of silver particles .…”

Section: Introductionmentioning

confidence: 99%

“…To understand and predict how AgNPs behave in various environments, it is essential considering the thermodynamics driving the dissolution of the material and how this phenomenon is related to the physicochemical properties of the particles and environmental conditions . Several factors such as composition of the dispersion medium, pH and oxidation state of Ag in the AgNPs have been shown to alter the properties and dissolution rates of silver particles . Therefore, investigation on the redox properties of silver particles and their reactivity at interfaces with liquid phases is highly desirable …”

Section: Introductionmentioning

confidence: 99%

“…[5] Several factors such as composition of the dispersion medium, pH and oxidation state of Ag in the AgNPs have been shown to alter the properties and dissolution rates of silver particles. [5] Therefore, investigationo nt he redox properties of silver particles and their reactivity at interfaces with liquid phases is highly desirable. [4b, 6] Utilisation of the AgNPsf or the abovementioned practical applicationso ften requires the construction of integrated chemicals ystems, and in most cases polymer-supported nanoparticlesa re employed.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Scanning Electrochemical Microscopy and Voltammetric Investigation of Silver Nanoparticles Embedded within a Nafion Membrane

2016

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In this paper, silver nanoparticles (AgNPs), incorporated in the poly(perfluorosulfonic) acid membrane Nafion® 117, were fabricated by chemical reduction of the Ag+-loaded membranes, using HCOH in a basic medium as reducing agent. The AgNPs content within the membrane varied in proportion of the concentration of AgNO3 used in the incorporation step of Ag+ in the ion-exchange. Information on size and density of the AgNPs within the matrix was obtained by SEM analysis. The size of the AgNPs varied between 10 and 20 nm, regardless of the AgNO3 concentration used for their preparation, while AgNPs density was the higher, the greater was the AgNO3 concentration in the solution. Information on the oxidation state of Ag in the AgNPs and their distribution and aggregation on the surface of the Nafion membranes were obtained by SECM measurements. The use of [Ir(Cl)6]3- and Ru(NH3)63+ as redox mediators allowed establishing whether the AgNPs were interconnected to create nano-chain networks to provide AgNPs-loaded Nafion membranes with electronic conductivity. Moreover, combination of SECM and anodic stripping voltammetry allowed establishing the reactivity of the AgNPs-Nafion composites in terms of Ag(I) species released at the nanocomposite/solution interface. These aspects are relevant for the potential application of these AgNPs-loaded membranes for antimicrobial protection purposes

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Silver nanoparticles in aquatic environments: Physiochemical behavior and antimicrobial mechanisms

Cited by 279 publications

References 437 publications

A review on preparation methods of SNPs and their biomedical applications

A review on preparation methods of SNPs and their biomedical applications

Co-exposure to silver nanoparticles and cadmium induce metabolic adaptation in HepG2 cells

Scanning Electrochemical Microscopy and Voltammetric Investigation of Silver Nanoparticles Embedded within a Nafion Membrane

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