Silver Nanoparticles in the Environment

doi:10.1007/978-3-662-46070-2

Cited by 23 publications

(3 citation statements)

References 80 publications

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“…As proven by in vitro experiments, nanosilver is capable of penetrating the cells of organisms and can be detected in high amounts in cytosol, endosomes, and lysosomes [9]. In human cell lines, exposure to AgNPs results in cytotoxicity and DNA damage, while in animal models nanosilver can affect multiple organs, cause reproductive system dysfunction, and alter brain functions [10][11][12][13]. Given the crucial role of the nervous system in the regulation of key vital functions, the neurotoxic potential of AgNPs has received special attention among researchers.…”

Section: Introductionmentioning

confidence: 99%

Coating-Dependent Neurotoxicity of Silver Nanoparticles—An In Vivo Study on Hippocampal Oxidative Stress and Neurosteroids

Dziendzikowska

Wilczak

Grodzicki

et al. 2022

IJMS

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Silver nanoparticles (AgNPs) are one of the most widely used nanomaterials. The level of exposure to nanosilver is constantly raising, and a growing body of research highlights that it is harmful to the health, especially the nervous system, of humans. The potential pathways through which nanosilver affects neurons include the release of silver ions and the associated induction of oxidative stress. To better understand the mechanisms underlying the neurotoxicity of nanosilver, in this study we exposed male Wistar rats to 0.5 mg/kg body weight of AgNPs coated with bovine serum albumin (BSA), polyethylene glycol (PEG), or citrate, or to AgNO3 as a source of silver ions for 28 days and assessed the expression of antioxidant defense markers in the hippocampus of the exposed animals after 1 week of spatial memory training. We also evaluated the influence of AgNPs coating on neurosteroidogenesis in the rat hippocampus. The results showed that AgNPs disrupted the antioxidant system in the hippocampus and induced oxidative stress in a coating-dependent manner, which could potentially be responsible for neurodegeneration and cognitive disorders. The analysis of the influence of AgNPs on neurosteroids also indicated coating-dependent modulation of steroid levels with a significant decrease in the concentrations of progesterone and 17α-progesterone in AgNPs(BSA), AgNPs(PEG), and Ag+ groups. Furthermore, exposure to AgNPs or Ag+ resulted in the downregulation of selected genes involved in antioxidant defense (Cat), neurosteroid synthesis (Star, Hsd3b3, Hsd17b1, and Hsd17b10), and steroid metabolism (Ar, Er1, and Er2). In conclusion, depending on the coating material used for their stabilization, AgNPs induced oxidative stress and modulated the concentrations of steroids as well as the expression of genes involved in steroid synthesis and metabolism.

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Section: Introductionmentioning

confidence: 99%

Coating-Dependent Neurotoxicity of Silver Nanoparticles—An In Vivo Study on Hippocampal Oxidative Stress and Neurosteroids

Dziendzikowska

Wilczak

Grodzicki

et al. 2022

IJMS

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“…The success of this method hinges on critical parameters such as the diameter and pore size of the packed materials, the choice of the appropriate eluent as the mobile phase, and the length of the column used. The versatility and effectiveness of size-exclusion chromatography make it a standout method among the most used techniques for size-based separations in phytochemical research [12,53].…”

Section: Isolation and Characterization Of Bioactive Compounds In Lit...mentioning

confidence: 99%

Advancements in Litchi chinensis Peel Processing: A Scientific Review of Drying, Extraction, and Isolation of Its Bioactive Compounds

Cano-Gómez,

Alonso-Castro,

Carranza-Alvarez

et al. 2024

Foods

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This article systematically reviews the advancements in processing litchi peel (Litchi chinensis), emphasizing drying, extraction, purification methods, and the potential of bioactive compounds obtained from litchi peel. This work also highlights the impact of various drying techniques on phytochemical profiles, focusing on how methods such as hot air and freeze-drying affect the preservation of bioactive compounds. The study delves into extraction methods, detailing how different solvents and techniques influence the efficiency of extracting bioactive compounds from litchi peel. Furthermore, the purification and characterization of active compounds, showcasing the role of chromatographic techniques in isolating specific bioactive molecules, is discussed. Biological properties and mechanisms of action, such as antioxidant, antihyperglycemic, cardioprotective, hepatoprotective, anti-atherosclerotic, and anticancer activities, are reviewed, providing insight into the potential health benefits of litchi peel compounds. This review highlights the importance of optimizing and selecting accurate drying and extraction methods to maximize the therapeutic effects of litchi peel and its bioactive compounds. This review also reveals the broad pharmacological potential of the isolated compounds, underscoring the need for further research to discover their specific actions and health benefits.

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“…The microbial culture medium is regenerative due to the presence of compounds such as tryptone and yeast extract, and it is useful alone for the biosynthesis of NCs [63]. In the BCS route, chemicals produced by bacteria secreted outside the cell in the culture medium are considered effective levers, and no bacterial cells are needed.…”

Section: Bcsmentioning

confidence: 99%

Methods of green synthesis of Au NCs with emphasis on their morphology: A mini-review

Sayadi

Akbarzadeh

Pourmardan

et al. 2021

Heliyon

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This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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Silver Nanoparticles in the Environment

Cited by 23 publications

References 80 publications

Coating-Dependent Neurotoxicity of Silver Nanoparticles—An In Vivo Study on Hippocampal Oxidative Stress and Neurosteroids

Coating-Dependent Neurotoxicity of Silver Nanoparticles—An In Vivo Study on Hippocampal Oxidative Stress and Neurosteroids

Advancements in Litchi chinensis Peel Processing: A Scientific Review of Drying, Extraction, and Isolation of Its Bioactive Compounds

Methods of green synthesis of Au NCs with emphasis on their morphology: A mini-review

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