Silver nanorods induced oxidative stress and chromosomal aberrations in the
            <i>Allium cepa</i>
            model

Durairaj, Karthiga; Roy, Barsha; Chandrasekaran, Natarajan; Krishnan, Suresh Palamadai; Mukherjee, Amitava

doi:10.1049/iet-nbt.2019.0224

Cited by 16 publications

(2 citation statements)

References 47 publications

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“…Durairaj, Roy, Chandrasekaran, Krishnan, and Mukherjee (2020) investigated the cell viability and different ROS assays of various concentrations (5, 10, and 15 μM) of Ag NRs using Allium cepa . They found that exposure to Ag NRs decreased in the mitotic index and an increased in the chromosomal aberrations such as chromosome break, disturbed metaphase, and anaphase bridge.…”

Section: Non‐magnetic Metallic Nanomaterialsmentioning

confidence: 99%

A review on nanotoxicity and nanogenotoxicity of different shapes of nanomaterials

Demir

2020

J of Applied Toxicology

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Nanomaterials (NMs) generally display fascinating physical and chemical properties that are not always present in bulk materials; therefore, any modification to their size, shape, or coating tends to cause significant changes in their chemical/physical and biological characteristics. The dramatic increase in efforts to use NMs renders the risk assessment of their toxicity highly crucial due to the possible health perils of this relatively uncharted territory. The different sizes and shapes of the nanoparticles are known to have an impact on organisms and an important place in clinical applications. The shape of nanoparticles, namely, whether they are rods, wires, or spheres, is a particularly critical parameter to affect cell uptake and site-specific drug delivery, representing a significant factor in determining the potency and magnitude of the effect. This review, therefore, intends to offer a picture of research into the toxicity of different shapes (nanorods, nanowires, and nanospheres) of NMs to in vitro and in vivo models, presenting an in-depth analysis of health risks associated with exposure to such nanostructures and benefits achieved by using certain model organisms in genotoxicity testing. Nanotoxicity experiments use various models and tests, such as cell cultures, cores, shells, and coating materials. This review article also attempts to raise awareness about practical applications of NMs in different shapes in biology, to evaluate their potential genotoxicity, and to suggest approaches to explain underlying mechanisms of their toxicity and genotoxicity depending on nanoparticle shape.

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Section: Non‐magnetic Metallic Nanomaterialsmentioning

confidence: 99%

A review on nanotoxicity and nanogenotoxicity of different shapes of nanomaterials

Demir

2020

J of Applied Toxicology

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“…1c). Stickiness, a chromatid type abnormality, is arisen from the inappropriate folding of inner chromatins into chromatids or depolymerization of chromosomes 21 . It is considered to be an irreversible chromosomal abnormality and usually result in death of the cells 35 .…”

Section: Resultsmentioning

confidence: 99%

Preventive efficiency of Cornelian cherry (Cornus mas L.) fruit extract in diniconazole fungicide-treated Allium cepa L. roots

Macar

Yalçın

et al. 2021

Sci Rep

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Cornelian cherry (Cornus mas L.) is a medicinal plant with antioxidant-rich fruits. Diniconazole, a broad-spectrum fungicide, is employed extensively. The present study was designed to evaluate the preventive efficiency of C. mas fruit extract (CME) against the toxic effects of diniconazole on a model organism, Allium cepa L. For this aim, physiological, cytogenetic and biochemical parameters as well as the meristematic cell damages were investigated in A. cepa treated with diniconazole and C. mas extract. A. cepa bulbs were divided into six groups which were treated with tap water, 0.5 g/L CME, 1.0 g/L CME, 100 mg/L diniconazole, 0.5 g/L CME + 100 mg/L diniconazole and 1.0 g/L CME + 100 mg/L diniconazole, respectively. Diniconazole application caused a significant reduction in germination percentage, root elongation and total weight gain. Mitotic index decreased, while chromosomal aberrations increased following diniconazole application. Diniconazole caused significant rises in malondialdehyde content and the total activities of superoxide dismutase and catalase enzymes. The meristematic cell damages induced by diniconazole were indistinct transmission tissue, epidermis cell deformation, thickening of the cortex cell wall and flattened cell nucleus. Aqueous C. mas extracts induced a dose-dependent prevention and amelioration in all damages arisen from diniconazole application.

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Unlocking the Potential of Nanoparticles in Regulation of Antioxidant Defense in Medicinal Plants Under Abiotic Stress Conditions

Gupta,

Seth,

Faizan

et al. 2024

Sustainable Landscape Planning and Natural Resources Management

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Silver nanorods induced oxidative stress and chromosomal aberrations in the Allium cepa model

Cited by 16 publications

References 47 publications

A review on nanotoxicity and nanogenotoxicity of different shapes of nanomaterials

A review on nanotoxicity and nanogenotoxicity of different shapes of nanomaterials

Preventive efficiency of Cornelian cherry (Cornus mas L.) fruit extract in diniconazole fungicide-treated Allium cepa L. roots

Unlocking the Potential of Nanoparticles in Regulation of Antioxidant Defense in Medicinal Plants Under Abiotic Stress Conditions

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