Silver sulfide coated alginate radioenhancer for enhanced X-ray radiation therapy of breast cancer

Mousazadeh, Navid; Seidi, Farzad; Ghaffarlou, Mohammadreza; Rashidzadeh, Hamid; Hosseinmirzaei, Ali; Mozafari, Faezeh; Danafar, Hossein; Nosrati, Hamed

doi:10.1016/j.ijbiomac.2023.123636

Cited by 7 publications

(1 citation statement)

References 58 publications

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“…Our systematic and rigorous approach to literature selection culminated in the inclusion of five pivotal studies 11 , 12 , 13 , 14 , 15 from an initial pool of 1245 records. The detailed process of identification, screening, and selection is visually illustrated in Figure 1 , depicting a clear path from the initial search to the final inclusion.…”

Section: Resultsmentioning

confidence: 99%

Comparative efficacy of silver alginate dressings versus standard gauze in enhancing wound healing post‐mastectomy for triple‐negative breast cancer: A systematic review and meta‐analysis

Qiang,

Jiang,

Xing

et al. 2023

International Wound Journal

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This meta‐analysis evaluates the efficacy of silver alginate dressings (SAD) compared to standard gauze (SG) in enhancing wound healing and reducing scar formation post‐mastectomy in patients with triple‐negative breast cancer. From an initial pool of 1245 articles, five studies met the inclusion criteria. The analysis revealed that SAD significantly improve early wound healing 1 week post‐mastectomy, as indicated by lower Redness, Edema, Ecchymosis, Discharge, and Approximation (REEDA) scales (I2 = 85%; Random: SMD: −7.08, 95% CI: −8.26 to −5.98, p < 0.01), compared to SG. Additionally, long‐term scar outcomes measured by the Manchester Scar Scale (MSS) 5 months post‐mastectomy showed a notable reduction in scar formation (I2 = 95%; Random: SMD: −12.97, 95% CI: −16.20 to −9.75, p < 0.01)) in the silver alginate group. The findings support the use of SAD in post‐mastectomy care for triple‐negative breast cancer patients but highlight the need for further research on long‐term safety and cost‐effectiveness.

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Section: Resultsmentioning

confidence: 99%

Comparative efficacy of silver alginate dressings versus standard gauze in enhancing wound healing post‐mastectomy for triple‐negative breast cancer: A systematic review and meta‐analysis

Qiang,

Jiang,

Xing

et al. 2023

International Wound Journal

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Radiosensitization of breast cancer cells with AgBiS₂ nanodots: Preparation and in vitro evaluations

Xue,

Pilehvar,

Afshari

et al. 2024

Applied Organom Chemis

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Radiotherapy (RT), which is a therapeutic treatment modality that is commonly used for cancer, employs high‐energy irradiation to induce the generation of reactive oxygen species (ROS) and to cause DNA damages. Nevertheless, the therapeutic efficacy of RT is predominantly constrained due to inadequate DNA damage in malignancies and deleterious impacts on healthy tissues. In the current study, bovine serum albumin (BSA)–coated AgBiS2 nanodots, also known as AgBiS2@ BSA nanodots, were developed for enhanced breast cancer treatment. This was accomplished by the use of an extremely simple and eco‐friendly method. Both scanning transmission electron microscopy (STEM) and scanning electron microscopy (SEM) images revealed that prepared nanoradiosensitizers, AgBiS2@ BSA, were spherical in shape and uniformly distributed. AgBiS2@ BSA nanodots possessed excellent biocompatibility and exhibit excellent monodispersity as well. Furthermore, in vitro assays such as MTT, colony formation assay, and intracellular ROS generation assay revealed the significant cell inhibitory impact of the produced AgBiS2@ BSA nanodots under X‐ray irradiation under X‐ray irradiation. Remarkably, the combined administration of AgBiS2@ BSA nanodots along with X‐ray irradiation increased ROS level within cells by increasing the localized radiation dosage and improving the anti‐tumor effectiveness of RT.

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Nanomaterials for enhanced X‐ray‐triggered cancer therapy: Progress and prospects

Chen,

Shangguan,

Lin

et al. 2024

BMEMat

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X‐rays, a form of ionizing radiation with high energy and significant penetration capability, are commonly used in clinical tumor treatment through radiotherapy. Despite their widespread use, optimizing X‐ray efficacy remains a critical challenge due to issues such as radiation resistance and damage to surrounding health tissues. Recent advancements in nanotechnology have introduced new opportunities and challenges in cancer diagnosis and treatment. This review summarizes the latest progress in nanomaterials for X‐ray‐triggered cancer therapy, highlighting their various advantages such as targeted delivery, reduced side effects, and enhanced therapeutic efficacy. We examine how nanomaterials, including metals, metal oxides, metal sulfides, metal fluorides, rare earth oxides, cluster compounds, metal‐organic frameworks, and nanohybrids, enhance the effectiveness of X‐ray‐triggered treatments. Furthermore, we address the current challenges and future prospects of efficient X‐ray‐triggered cancer therapy, aiming to provide a comprehensive overview for researchers and clinicians in the field.

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Silver sulfide coated alginate radioenhancer for enhanced X-ray radiation therapy of breast cancer

Cited by 7 publications

References 58 publications

Comparative efficacy of silver alginate dressings versus standard gauze in enhancing wound healing post‐mastectomy for triple‐negative breast cancer: A systematic review and meta‐analysis

Comparative efficacy of silver alginate dressings versus standard gauze in enhancing wound healing post‐mastectomy for triple‐negative breast cancer: A systematic review and meta‐analysis

Radiosensitization of breast cancer cells with AgBiS₂ nanodots: Preparation and in vitro evaluations

Nanomaterials for enhanced X‐ray‐triggered cancer therapy: Progress and prospects

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Silver sulfide coated alginate radioenhancer for enhanced X-ray radiation therapy of breast cancer

Cited by 7 publications

References 58 publications

Comparative efficacy of silver alginate dressings versus standard gauze in enhancing wound healing post‐mastectomy for triple‐negative breast cancer: A systematic review and meta‐analysis

Comparative efficacy of silver alginate dressings versus standard gauze in enhancing wound healing post‐mastectomy for triple‐negative breast cancer: A systematic review and meta‐analysis

Radiosensitization of breast cancer cells with AgBiS2 nanodots: Preparation and in vitro evaluations

Nanomaterials for enhanced X‐ray‐triggered cancer therapy: Progress and prospects

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Product

Resources

About

Radiosensitization of breast cancer cells with AgBiS₂ nanodots: Preparation and in vitro evaluations