Silyl-functionalised silver rhodium and iridium N-heterocyclic carbene complexes with promising cytotoxicity and antimicrobial potential

Synthesis and a combined experimental/theoretical structural study of a comprehensive set of Pd/NHC complexes witho-,m-, andp-halogen-substituted aryl groups (X = F, Cl, Br, CF3)

“…32 Tuning biological activity is the key application of functional group effects in the medicinal and pharmaceutical applications of Pd/NHC complexes. [33][34][35][36][37][38] Recent studies have highlighted the exceptional potential of M/NHC systems in life sciences and drug design. [39][40][41][42] The ability to introduce electron-withdrawing halogen atoms in general and highly specific F-substituents in particular [43][44][45][46] is undoubtedly highly important for this area of research.…”