“…This fact illustrates the utility of our approach. Furthermore, from Table IV, we surprisingly find that Rabbit-Mouse, Rabbit-Rat and Rat-Mouse have smaller entries which didn't appear in [15], [29]- [34]. But this result coincided with result of phylogenetic tree [35] .…”
Section: Discussionsupporting
confidence: 66%
“…Moreover, compared with others' work [1]- [5], [8]- [14], [19]- [28], our graphical curves are compact, that's to say, our graphical curves do not take up much room, and the complexities of computation is very small. Furthermore, the examination of similarities among the full coding sequences of globin gene of different species (see Table I) which were studied by Li et al [15] and Guo et al [29] and Li et al [30] and Qi et al [31] and Huang et al [32] and Guo et al [33] and Qi et al [34] shows our graphical representation method is more effective to the comparative study of DNA sequences.…”
“…This fact illustrates the utility of our approach. Furthermore, from Table IV, we surprisingly find that Rabbit-Mouse, Rabbit-Rat and Rat-Mouse have smaller entries which didn't appear in [15], [29]- [34]. But this result coincided with result of phylogenetic tree [35] .…”
Section: Discussionsupporting
confidence: 66%
“…Moreover, compared with others' work [1]- [5], [8]- [14], [19]- [28], our graphical curves are compact, that's to say, our graphical curves do not take up much room, and the complexities of computation is very small. Furthermore, the examination of similarities among the full coding sequences of globin gene of different species (see Table I) which were studied by Li et al [15] and Guo et al [29] and Li et al [30] and Qi et al [31] and Huang et al [32] and Guo et al [33] and Qi et al [34] shows our graphical representation method is more effective to the comparative study of DNA sequences.…”
“…12, 13 26,27,28,29,30). Since many authors use slightly different data for β-globin gene, the locations of different subsequences in this gene and their full description listed in the tables may be helpful for some alternative similarity studies.…”
Section: Discussionmentioning
confidence: 99%
“…24,25,27) for the sequences listed in Table 17 (histone H4 coding sequences). Table 16 Figures 21,22,23,24,25,26,27,28,29 are plotted in the same way as it has been done in chapter 2 (Figs. 1, 2, 3).…”
“…There is a variety of numerical alignment-free methods (for a review up to 2003 see [20]). Recently new numerical alternative methods have been developed, as for example [21][22][23][24][25][26][27][28][29][30][31]. Another group within numerical alignment-free methods are multidimensional graphical representations.…”
New approaches aiming at a detailed similarity/dissimilarity analysis of DNA sequences are formulated. Several corrections that enrich the information which may be derived from the alignment methods are proposed. The corrections take into account the distributions along the sequences of the aligned bases (neglected in the standard alignment methods). As a consequence, different aspects of similarity, as for example asymmetry of the gene structure, may be studied either using new similarity measures associated with four-component spectral representation of the DNA sequences or using alignment methods with corrections introduced in this paper. The corrections to the alignment methods and the statistical distribution moment-based descriptors derived from the four-component spectral representation of the DNA sequences are applied to similarity/dissimilarity studies of β-globin gene across species. The studies are supplemented by detailed similarity studies for histones H1 and H4 coding sequences. The data are described according to the latest version of the EMBL database. The work is supplemented by a concise review of the state-of-art graphical representations of DNA sequences.
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