Simple detection of potential pollutant effects on fungal growth, sclerotia formation and germination

Rogers, John E.; Li, S. W.

doi:10.1007/bf01609793

Cited by 4 publications

(5 citation statements)

References 12 publications

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“…High concentrations of copper have also been reported to inhibit sclerotia formation in A . oryzae G15 strain ( Long et al, 2017 ) and an Aspergillus strain ( Rogers and Li, 1985 ). These findings indicate the inhibitory effects of copper on sclerotia formation in A .…”

Section: Discussionmentioning

confidence: 99%

“…Copper has been suggested to inhibit sclerotia formation in the A . oryzae G15 strain ( Long et al, 2017 ) and in an Aspergillus strain ( Rogers and Li, 1985 ). In contrast, copper induces sclerotia formation in Penicillium thomii ( Zhang et al, 2014 ; Zhao et al, 2014 ).…”

Section: Introductionmentioning

confidence: 99%

“…In addition to this genetic evidence, the effects of copper treatment on sclerotia development have also been reported. Copper has been suggested to inhibit sclerotia formation in the A. oryzae G15 strain (Long et al, 2017) and in an Aspergillus strain (Rogers and Li, 1985). In contrast, copper induces sclerotia formation in Penicillium thomii (Zhang et al, 2014;Zhao et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

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Trace copper-mediated asexual development via a superoxide dismutase and induction of AobrlA in Aspergillus oryzae

Katayama

Maruyama²

2023

Front. Microbiol.

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The filamentous fungus Aspergillus oryzae, in which sexual reproduction remains to be discovered, proliferates mainly via asexual spores (conidia). Therefore, despite its industrial importance in food fermentation and recombinant protein production, breeding beneficial strains by genetic crosses is difficult. In Aspergillus flavus, which is genetically close to A. oryzae, structures known as sclerotia are formed asexually, but they are also related to sexual development. Sclerotia are observed in some A. oryzae strains, although no sclerotia formation has been reported in most strains. A better understanding of the regulatory mechanisms underlying sclerotia formation in A. oryzae may contribute to discover its sexual development. Some factors involved in sclerotia formation have been previously identified, but their regulatory mechanisms have not been well studied in A. oryzae. In this study, we found that copper strongly inhibited sclerotia formation and induced conidiation. Deletion of AobrlA encoding a core regulator of conidiation and ecdR involved in transcriptional induction of AobrlA suppressed the copper-mediated inhibition of sclerotia formation, suggesting that AobrlA induction in response to copper leads not only to conidiation but also to inhibition of sclerotia formation. In addition, deletion of the copper-dependent superoxide dismutase (SOD) gene and its copper chaperone gene partially suppressed such copper-mediated induction of conidiation and inhibition of sclerotia formation, indicating that copper regulates asexual development via the copper-dependent SOD. Taken together, our results demonstrate that copper regulates asexual development, such as sclerotia formation and conidiation, via the copper-dependent SOD and transcriptional induction of AobrlA in A. oryzae.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Trace copper-mediated asexual development via a superoxide dismutase and induction of AobrlA in Aspergillus oryzae

Katayama

Maruyama²

2023

Front. Microbiol.

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“…Traditional Persian medicine (PM) is based on two main principles, holistic viewpoints (4) and personalized medicine, that is called "Mizaj" or temperament (5).…”

Section: Introductionmentioning

confidence: 99%

“…Although there are a number of studies based on PMsuggested treatments for a variety of diseases (6)(7)(8), surveys for organizing its diagnostic criteria are rare (5).Written references of PM proposed some Mizaj assessment indices and named them the "ten criteria" (Ajnase-Ashareh) of Mizaj identifiers (9); each of them should be assessed in two fields ranging from extreme warm to extreme cold and also from extreme wet to extreme dry to define the entire body's Mizaj (10).…”

Section: Introductionmentioning

confidence: 99%

The Relationship Between Mizaj and Its Indices in Persian Medicine

Mojahedi

Alipour

Mozaffarpur

2018

Iran Red Crescent Med J

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Background: As personalized medicine is developing, similar concepts in Persian medicine need standardization. Objectives: The aim of this study was to compare the correlation of ten criteria of Mizaj assessment with Mizaj determined by experts. Methods: In this cross-sectional methodological research, 74 medical student volunteers were examined by 10 expert raters. The agreement between each ten indices and total Mizaj were assessed with the spearman correlation coefficient (r) and weighted by the kappa coefficient (wk). Results: Among ten indices, the largest agreement was observed amongst indices of psychic function, impressibility, physical function and physique with total warm or cold Mizaj and thus amongst indices of muscle and fat mass, touch and physique with total

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