1974
DOI: 10.1080/00039896.1974.10666548
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Simple Siliceous Pneumoconiosis in Negev Bedouins

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Cited by 66 publications
(20 citation statements)
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“…This circumstance together with the statistically significant connection between the presence of dustladen macrophage aggregates and such fibrotic conditions that are not related to echinococcosis and chronic pneumonia in our material, warrants the diagnosis of silicosis. Siliceous pneumoconiosis in people living in the North Saharan deserts has not been considered as a clinically significant condition, partly since the classic silicotic type of fibrosis was not present (POLICARD and COLLET, 1952;BAR-ZIV and GOLDBERG, 1974). The clinical significance of silicosis in camels, however, cannot be assessed from the present material.…”
Section: Discussionmentioning
confidence: 73%
“…This circumstance together with the statistically significant connection between the presence of dustladen macrophage aggregates and such fibrotic conditions that are not related to echinococcosis and chronic pneumonia in our material, warrants the diagnosis of silicosis. Siliceous pneumoconiosis in people living in the North Saharan deserts has not been considered as a clinically significant condition, partly since the classic silicotic type of fibrosis was not present (POLICARD and COLLET, 1952;BAR-ZIV and GOLDBERG, 1974). The clinical significance of silicosis in camels, however, cannot be assessed from the present material.…”
Section: Discussionmentioning
confidence: 73%
“…In some of them, a fibrotic reaction of the lung parenchyma in terms of silicosis has been reported [16]. These observations have been interpreted as typical morphological findings of silica containing dust deposits due to sand dust inhalation during desert storms, a characteristic observation in recent populations of the Sahara and Negev deserts [2,13]. The latter study [13] also clearly demonstrated the presence of silica crystals in the affected lung tissue by radiodiffraction analysis, so that it seems fair to assume that our historic patient suffered from the same condition, although we could not prove the presence of silica crystals in our patient by chemical or radiodiffraction methods.…”
Section: Discussionmentioning
confidence: 87%
“…Increased collagen is frequently observed in the lungs of cigarette smokers,5355 and irregular opacities reflecting this fibrosis can be observed on their chest X-rays comparable to those in pneumoconioses 23,5658. Collagen deposition and fibrosis in the human lung have been described following exposure to ambient air pollution particles,59 environmental exposure to crustal particles (eg, windstorms),60,61 and inhalation of emission source particles 62. This fibrogenic property of particles is exploited therapeutically with the instillation of gram quantities of a mineral oxide (ie, talc) particle into the pleural space to provide sclerosis 63…”
Section: Particle-related Lung Injurymentioning
confidence: 99%