Simple surface sulfonation retards plasticiser migration and impacts upon blood/material contact activation processes

Abstract

The simple sulfonation process significantly retards the migration of DEHP and is associated with the moderation of contact activation processes.

Plasticizer Motion and Diffusion

“…• use of non-migrating plasticizers 56,68 • application of nanocomposites and platelet fillers 24,60,63 • plasma surface modification (produces crosslinked surface which reduces migration) 37 • surface grafting of materials of low permeability 38 • PVC treatment with poly(azido acrylates) 64 • use of covalently bound plasticizers 62 • surface coating with materials of low permeability 52 • surface sulfonation of medical products 66 • photocrosslinking 44 • crosslinking in bulk 46,50 • complexing (additives which form links with plasticizers) 49 • annealing (reorganization and crystallization affect migration) 55 The migration studies are affected by several parameters which include simulant, temperature, size (and especially thickness) of sample, and ratio of sample volume to simulant volume. Especially proper selection of simulants is very important for usefulness of test results.…”