Simplex optimisation of electroanalytical experiments

Oduoza, Chike F.

doi:10.1016/0169-7439(92)90051-g

Cited by 6 publications

(2 citation statements)

References 7 publications

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“…HCl was chosen as the supporting electrolyte based on the investigations carried out by Friestad and Bronstad [15,16]. Other factors, such as the voltage step, pulse amplitude, voltage step time and the pulse time were chosen as suggested by the literature [18][19][20][21]. However, these factor levels were defined based on previous univariate studies.…”

Section: Voltammetric Parametersmentioning

confidence: 99%

“…Nevertheless its sensitivity is not sufficient for practical application in natural sample monitoring. However, the sensitivity of the technique can be increased by optimization using chemometric approaches such as the use of factorial designs, response surface methodology (RSM) [17][18][19], or by the sequential simplex method [20]. In a preliminary recent study [21], a reasonable sensitivity for glyphosate determination was reached by applying experimental designs in the optimization of a method using square wave voltammetry (SWV); however, in that study no application in natural samples was realized.…”

Section: Introductionmentioning

confidence: 99%

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Glyphosate Determination in Soil, Water and Vegetables Using DPV Optimized by Response Surface Methodology

Teófilo¹,

Reis²,

Reis³

et al. 2007

Port. Electrochim. Acta

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A voltammetric procedure optimized by experimental design for glyphosate determination in soil, water and vegetable samples is described. The voltammetry experiments were performed using a hanging mercury drop electrode (HMDE). The DPV variables involved in the optimization process were: voltage step, pulse amplitude, pulse interval, voltage step time and concentration of the supporting electrolyte. A full 2 5 factorial design was chosen to evaluate these effects. From the results obtained by the factorial design the three most important factors were determined. These variables were evaluated with a central composite design. Under the optimized conditions, the operational range was from 0.050 to 100.0 mg dm-3 and the detection and quantification limits were 14 and 48 µg dm-3 , respectively. The optimized method was successfully applied to glyphosate determination in soil, water and vegetables after purifying with an ion exchange resin and derivation.

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Section: Voltammetric Parametersmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Glyphosate Determination in Soil, Water and Vegetables Using DPV Optimized by Response Surface Methodology

Teófilo¹,

Reis²,

Reis³

et al. 2007

Port. Electrochim. Acta

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Profiling of 3,4-methylenedioxymethamphetamine by means of high-performance liquid chromatography

Byrska

Zuba

2007

Anal Bioanal Chem

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An impurity-profiling method for 3,4-methylenedioxymethamphetamine (MDMA) is presented. The impurities of interest were extracted by solid-phase extraction (SPE) on Bakerbond C18 spe columns from a weakly alkaline solution (pH 8.5). Development of the extraction conditions covered selection of the buffer for dissolution of the sample and the volume of the eluent used to elute the impurities. An important part of the studies was to optimise the separation conditions, and the simplex method was used for this purpose. Cluster analysis was applied for comparison of samples and its grouping. The developed method was based on the areas of 33 selected peaks corresponding to MDMA impurities. All examined samples were correctly classified into clusters corresponding to the synthetic route.

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Design of an intelligent electrochemical system using cybernetic instrumentation

Oduoza

Fielden

Miller

1996

Laboratory Automation & Information Management

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Simplex optimisation of electroanalytical experiments

Cited by 6 publications

References 7 publications

Glyphosate Determination in Soil, Water and Vegetables Using DPV Optimized by Response Surface Methodology

Glyphosate Determination in Soil, Water and Vegetables Using DPV Optimized by Response Surface Methodology

Profiling of 3,4-methylenedioxymethamphetamine by means of high-performance liquid chromatography

Design of an intelligent electrochemical system using cybernetic instrumentation

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