Simplified physiologic management of status asthmaticus in children

A 25-year perspective of status asthmaticus

“…There may be only a relatively "closed system" in asthmatics, in that the nonmetabolic increase in CO2 can be rapidly eliminated as illustrated by the CHPgh studies. 35 Moreover, in asthma a slow infusion of a 2:3 isotonic infusion (isotonic = 3 mEq/kg) is given instead of a rapid infusion of hypertonic NaHCO3 as is given to infants.…”