Abstract. Epitaxial growth of SiGe quantum cascade (QC) lasers has thus far proved difficult, and nonabrupt Ge profiles are known to exist. We model the resulting barrier degradation by simulating annealing in pairs of quantum wells (QWs). Using a semiclassical charge transport model, we calculate the changes in scattering rates and transition energy between the lowest pair of subbands.We compare results for each of the possible material configurations for SiGe QC lasers. The effects are most severe in n-type (001) Si-rich systems due to the large effective electron mass, and in p-type systems due to the coexistence of light-and heavy-holes.The lower effective mass and conduction band offset of (111) oriented systems minimises transition energy variation, and a large interdiffusion length (L d = 1.49 nm) is tolerated with respect to scattering rate. Ge-rich systems are shown to give the best tolerance with respect to subband separation (L d = 3.31 nm), due also to their low effective mass.