Simulated cancer of the lower lip attributed to a “caliber persistent” artery

Abstract

Observations arc reported on three lesions of the lower lip simulating cancer in elderly men and attributed to caliber persistent arteries. Persistent caliber arteries are those with a diameter larger than normal near a mucosal or external surface. Caliber persistency of the lip artery is best characterized by a quotient, using the distance from the border between epithelium and connective tissue as numerator, and its diameter as denominator. A quotient lower than 1.6 to 1.7 may be regarded as indicative of this vascular anomaly.

Calibre Persistent Labial Artery: Clinical Features and Immunohistochemistry Diagnosis

“…The authors described arteries with a diameter larger than normal, near a mucosal or external surface, which were similar to the lesions described in the gastrointestinal tract [2,3].…”

Caliber persistent artery of the eyelid

“…Both pass through the rigid osseous canals just as the inferior alveolar artery does and hence may maintain vessel diameter beyond the point of exit from its osseous canals. An alternative theory is that this represents an ageing change and that intense sun exposure combined with senile atrophy of the tissues results in vascular ectasia [4][5][6]. Given the relatively young age of our patients, this second theory seems less attractive.…”

“…CPA has also been described at other sites in the gastrointestinal tract [2,3]. However, this entity is best recognized on the skin of the lower lip [4][5][6][7][8][9][10]. Herein we report three cases of caliber persistent artery occurring on the eyelid, one of which was bilateral.…”

“…In the lips, it has been suggested that this is a developmental abnormality where the inferior alveolar artery retains its large size [4]. The artery walls are thickened and continue to undergo thickening even after it has left the bone through the mental foramen traveling towards the orbicularis oris muscle to supply the mucosal aspect of the lower lip, resulting in a CPA.…”

Caliber persistent artery in the anterior palate of an Egyptian patient with type-2 diabetes mellitus: a rare case report

“…Being idiopathic in nature and rare in incidence, predisposing factors included intense sun exposure, senile atrophy of tissue associated with vascular ectasia, secondary to ageing, and injury from long-term pipe smoking. 6,7 Although caliber-persistent artery is neither totally plausible nor delineated, it fits the best There appears a dysregulated hematopoietic element induced a low-grade irritation causing the arterial wall to thicken, which made the site liable to ulceration in the harsh oral environment. Either idiopathically induced or pathophysiologically caused by the underlying diabetic condition, the poorly vascularized anterior palate might contribute to the severity of the condition.…”