:In this study, we investigated the statistical occupations and interannual variations of land cover types over Northeast Asian region using the 12 years (2001-2012) MODerate Resolution Imaging Spectroradiometer(MODIS) land cover data sets. The spatial resolution and land cover types of MODIS land cover data sets are 500 m and 17, respectively. The 12-year average shows that more than 80% of the analysis region is covered by only 3 types of land cover, cropland (36.96%), grasslands (23.14%) and mixed forests (22.97%). Whereas, only minor portion is covered by cropland/natural vegetation mosaics (6.09%), deciduous broadleaf forests (4.26%), urban and built-up (2.46%) and savannas (1.54%). Although sampling period is small, the regression analysis showed that the occupations of evergreen needleleaf forests, deciduous broadleaf forests and mixed forests are increasing but the occupations of woody savannas and savannas are decreasing. In general, the pixels where the land cover types are classified differently with year are amount to more than 10%. And the interannual variations in the occupations of land cover types are most prominent in cropland (1.41%), mixed forests (0.82%) and grasslands (0.73%). In addition, the percentage of pixels classified as 1 type for 12 years is only 57% and the other pixels are classified as more than 2 types, even 9 types. The annual changes in the classification of land cover types are mainly occurred at the almost entire region, except for the eastern and northwestern parts of China, where the single type of land cover located. When we take into consider the time scale needed for the land cover changes, the results indicate that the MODIS land cover data sets over the Northeast Asian region should be used with caution.