Simulated moving‐bed reactor: Reactive–separation regions

Minceva, Mirjana; Rodrigues, Alı́rio E.

doi:10.1002/aic.10532

Cited by 15 publications

(6 citation statements)

References 36 publications

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“…A case study-Optimization of a True Moving Bed Reactor True moving bed reactor (TMBR) is a multifunctional unit that is capable of integrating reaction and separation simultaneously, being an alternative to the traditional way of production where it is found one specific unit for each step (reaction and separation) of the production route. It is highlighted as an efficient way to leverage the potential of systems in which the reactions are limited by equilibrium [23][24][25][26]. The equilibrium conversion is not a limitation in those units because one or more of the products are continuously removed from the reaction zone [27].…”

Section: Benchmark 4-egg Crate Function Constrainedmentioning

confidence: 99%

From an Optimal Point to an Optimal Region: A Novel Methodology for Optimization of Multimodal Constrained Problems and a Novel Constrained Sliding Particle Swarm Optimization Strategy

et al. 2021

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The present work proposes a novel methodology for an optimization procedure extending the optimal point to an optimal area based on an uncertainty map of deterministic optimization. To do so, this work proposes the deductions of a likelihood-based test to draw confidence regions of population-based optimizations. A novel Constrained Sliding Particle Swarm Optimization algorithm is also proposed that can cope with the optimization procedures characterized by multi-local minima. There are two open issues in the optimization literature, uncertainty analysis of the deterministic optimization and application of meta-heuristic algorithms to solve multi-local minima problems. The proposed methodology was evaluated in a series of five benchmark tests. The results demonstrated that the methodology is able to identify all the local minima and the global one, if any. Moreover, it was able to draw the confidence regions of all minima found by the optimization algorithm, hence, extending the optimal point to an optimal region. Moreover, providing the set of decision variables that can give an optimal value, with statistical confidence. Finally, the methodology is evaluated to address a case study from chemical engineering; the optimization of a complex multifunctional process where separation and reaction are processed simultaneously, a true moving bed reactor. The method was able to efficiently identify the two possible optimal operating regions of this process. Therefore, proving the practical application of this methodology.

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Section: Benchmark 4-egg Crate Function Constrainedmentioning

confidence: 99%

From an Optimal Point to an Optimal Region: A Novel Methodology for Optimization of Multimodal Constrained Problems and a Novel Constrained Sliding Particle Swarm Optimization Strategy

et al. 2021

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“…The proposed model was successfully validated with experimental data, and the optimization tool was created to design the equipment geometry and process parameters in accordance to very high conversion and product purity (> 99 % and > 95 %, respectively). Minceva and Rodrigues [107] also proposed a model with an implemented TMBR analogy in order to determine reaction-separation regions of the system. Kawase et al [108] suggested the use of SMBR for the production of lactosucrose by reversible reaction of sucrose and lactose with the use of the free enzyme b-furanosidase.…”

Section: Enzymatic Reactive Chromatographymentioning

confidence: 99%

Reactive Separations for In Situ Product Removal of Enzymatic Reactions: A Review

Fellechner

Blatkiewicz

Смирнова

2019

Chemie Ingenieur Technik

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The topic of integrating enzymatic reactions with in situ product removal is addressed. Different integrated reactive separations structured accordingly to the corresponding unit operations, i.e., reactive distillation, reactive chromatography, reactive crystallization, and extractive biocatalysis, are discussed. Special attention is given to their realization with homogenous and heterogeneous biocatalysis. Various enzyme immobilization techniques are presented and distinct strategies for installation of heterogeneous catalysts into process equipment are discussed.

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“…The enzymatic sucrose inversion is an excellent test reaction to be used as an application for the purpose of modeling, design and optimization of chromatographic reactors, specifically those of SMB type. In that sense some studies have been conducted [40][41][42]. An overview of the works performed considering the SMBR process for the inversion of sucrose and separation of glucose/fructose are presented in Tab.…”

Section: Inversion Of Sucrosementioning

confidence: 99%

Chromatographic Reactors

2012

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Chromatographic reactors combining reaction and separation processes in a single unit of equipment are a way of achieving process intensification, which can lead to better energy efficiency, productivity improvement, and lower solvent consumption. In this review, two technologies for the implementation of chromatographic reactors, the simulated moving-bed reactor and the pressure swing adsorptive reactor will be discussed with examples from liquid phase processes: green fuels (acetals) and solvents (ethyl lactate), petrochemicals (isomerization/ separation of xylenes) and sugars (inversion of sucrose, glucose isomerization); and gas phase processes: hydrogen production from steam methane reforming with carbon dioxide capture.

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Simulated moving‐bed reactor: Reactive–separation regions

Cited by 15 publications

References 36 publications

From an Optimal Point to an Optimal Region: A Novel Methodology for Optimization of Multimodal Constrained Problems and a Novel Constrained Sliding Particle Swarm Optimization Strategy

From an Optimal Point to an Optimal Region: A Novel Methodology for Optimization of Multimodal Constrained Problems and a Novel Constrained Sliding Particle Swarm Optimization Strategy

Reactive Separations for In Situ Product Removal of Enzymatic Reactions: A Review

Chromatographic Reactors

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