This article aims to analyze the energy efficiency of combining heat pumps with photovoltaic (PV) panels in energy-efficient homes. The research methodology involved a detailed energy balance analysis, assessment of the impact of mechanical ventilation, location, heat loss, and the choice and operation of heat sources, with a particular focus on heat pumps in synergy with PV installations. The results demonstrate that integrating heat pumps with PV panels can significantly reduce the demand for external energy sources and lower the operating costs of buildings, while contributing to their energy self-sufficiency. This study highlights that such a combination of technologies is key to promoting sustainable development and achieving energy efficiency goals in the residential sector. The results of this analysis expand knowledge about the effectiveness of such systems and provide practical recommendations for designers and engineers interested in implementing renewable energy technologies in modern energy-efficient buildings, taking into account the impact of these solutions on reducing CO2 emissions as well.