Airtight blast door, as one of the key components of a rescue device or a ventilating device in underground coal mine, which can not only guarantee the normal operation ventilation system, but also can prevent the propagation of shock wave and invasion of toxic gases. Therefore, high structural stability and safety is fundamental when designing a door. An airtight blast door was developed and optimized based on static analysis and topological optimization, and dynamic response analysis of the optimized airtight blast door subjected to gas explosion load was conducted using a novel approach proposed in this paper-the FEM-SPH contact algorithm. Results showed that the main component weight of this kind of door is 27.4 % smaller than the original one without reducing the blast and impact behavior, the maximum displacement and stress of the optimization door obtained by FEM-SPH contact algorithm (dynamic response) are much larger than those using static mechanical analysis. The FEM-SPH contact algorithm and typical optimization method as well as the example presented in this paper are helpful for the original design and optimization of other products. Some conducive suggestions were recommended based on the simulation results.Consequently, to develop an airtight blast door with excellent antiknock feature and stable sealing performance is of great necessity for rescue effectiveness.Nowadays, the design and development for airtight blast door has not yet attracted enough attention as for coal mine refuge shelters. Currently, many large equipment manufacturing companies, such as Mine ARC Systems, Shairzal Safety Engineering, Jack Kennedy Metal Products, Modern Mine Safety, Supply LLC, have been committed to design and safety evaluation of such a device [5]. In China, the government has made some relevant standards which demanded that all coal mines must be equipped with rescue equipment [6]. An airtight blast door must be stable and flexible so as to resist shock wave caused by gas explosion. Distortions and plastic deformations are not allowed in critical components, such as the observation windows, stiffeners and ribs. Of course, numerous studies have been performed on antiknock performance of blast door, on purpose of revealing its deformation mechanism and structural safety subjected to an explosion blast load [7]. The two commonly used approaches to examine the antiknock performance of the device are to conduct blast tests and numerical analysis, respectively. Fan [8] and Guo [9] carried out an experiment in a full-scale tunnel to test the anti-shock performance of recue capsule in a 40 m and 100 m tunnel with the explosion load of 200 m 3 of gas/air mixture, the pressure value at different positions in real tunnel and the limitation of gas overpressure on the surface of the blast door are obtained. Continuously, some similar experiments have been implemented on the antiknock performance under different types of explosive loads by few researchers [10][11][12][13][14][15]. However, on one hand, it is expensive and...