Simulation of breast compression in mammography using finite element analysis: A preliminary study

Liu, Yan Lin; Liu, Pei Yuan; Huang, Mingliang; Han, Ruo Ping; Wu, Jen-Ming

doi:10.1016/j.radphyschem.2017.01.017

Cited by 10 publications

(9 citation statements)

References 22 publications

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“…4(b,c) respectively. The reaction force experienced by the fixed plate was found to be ~100 N for the breast body, which corroborates well with the clinical compression force 25 . The resultant compressed breast 3D surfaces for patients 06L, 08L, 08R, 10R, and 14L can be found in our dataset “deformed breast atlas” folder.…”

Section: Methodssupporting

confidence: 80%

Optical breast atlas as a testbed for image reconstruction in optical mammography

Xing

Duan²,

Indurkar

et al. 2021

Sci Data

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We present two optical breast atlases for optical mammography, aiming to advance the image reconstruction research by providing a common platform to test advanced image reconstruction algorithms. Each atlas consists of five individual breast models. The first atlas provides breast vasculature surface models, which are derived from human breast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) data using image segmentation. A finite element-based method is used to deform the breast vasculature models from their natural shapes to generate the second atlas, compressed breast models. Breast compression is typically done in X-ray mammography but also necessary for some optical mammography systems. Technical validation is presented to demonstrate how the atlases can be used to study the image reconstruction algorithms. Optical measurements are generated numerically with compressed breast models and a predefined configuration of light sources and photodetectors. The simulated data is fed into three standard image reconstruction algorithms to reconstruct optical images of the vasculature, which can then be compared with the ground truth to evaluate their performance.

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Section: Methodssupporting

confidence: 80%

Optical breast atlas as a testbed for image reconstruction in optical mammography

Xing

Duan²,

Indurkar

et al. 2021

Sci Data

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“…The breast density, which is considered an essential element by the previous studies, it was also noted that the Percent Mammographic Density (PMD) (expressed as a percentage of the breast area) associated with many risk factors, notably including BMI, parity, and gravida, and menopausal status, that are mainly associated with variations in mammographic density, and in addition, we are also associated with differences in one or more of these tissue features 22 . Thereby, it was shown previously in researches that parity and gravida status were inversely and significantly associated with breast tissue density and collagen percent 23 .…”

Section: Discussionmentioning

confidence: 95%

Mammographic density and its association with molecular subtype of breast cancer.

Jabeen¹,

Rasheed²,

Imran³

et al. 2020

Int. j. endorsing health sci. res.

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Background: Breast cancer is the leading cause of death in women globally. The present study aimed to determine the prevalence of different mammographic density of breast parenchyma along with the association with the molecular subtype of breast cancer. Methodology: The present cross-sectional study was conducted among breast cancer females age 40 and above. The study participants' demographic and clinical data, such as age, sex, menstrual status, gravida, parity, and lactation, were collected using a standard questionnaire. The anthropometric parameters were taken by using the standard techniques. Breast physical examination, mammography, and ultrasound were done. The ultrasound did the breast tumor biopsy -guided techniques and histopathology, and immunohistochemistry was used to identify the molecular subtype of breast cancer. The univariate and multivariate statistic was performed on SPSS version 20.0. Results: Most of the patients<50 years were human epidermal growth factor receptor (HER2), estrogen receptor (ER), progesterone receptor (PR) positive, and are overweight too. Similar findings were noted among lactating and multigravida patients. The Grade I tumor and dense breast patients were 100% with HER2 negative and ER, PR positive. Most heterogeneous dense and fibroglandular containing breast patients were ER, PR positive. There is a significant correlation between BMI, microcalcification, and HER2 positive. Most of the triple Negative and Luminal-B were heterogeneous dense. Conclusion: In conclusion, a significant association between the mammographic density parameters and molecular breast cancer subtype, particularly Luminal-A and luminal B, was seen. The ER, PR, and HER-2 have a positive correlation with the physical radiographical and mammodensity parameters.

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“…The model developed in this work specifies the inner part of the prosthesis using the biomimetic technique. [13,15,23,47,48]. These properties can be obtained using medical grade silicone with different configurations spaces (Softgel A-341C-DC 200 silicone); silicone has been widely used for the development of prostheses because it is not toxic, and it is biocompatible with the human body, withstanding common sterilization methods.…”

Section: Model Fem: Modeling and Analysis In Finite Elementmentioning

confidence: 99%

“…For the internal structure, a hyper elastic nonlinear material (Neo-Hookean) was considered with a Young modulus of 15 Kpa, Poisson modulus of 0.4 and damping ratio values (ζ) of 0.06, similar to the properties of glandular tissue. In addition, properties of fatty tissue of 2.5 Kpa, Poisson modulus of 0.499 and damping ratio values (ζ) of 0.06 were considered for the interior [13,15,23,47,48]. These properties can be obtained using medical grade silicone with different configurations spaces (Softgel A-341C-DC 200 silicone); silicone has been widely used for the development of prostheses because it is not toxic, and it is biocompatible with the human body, withstanding common sterilization methods.…”

Section: Model Fem: Modeling and Analysis In Finite Elementmentioning

confidence: 99%

“…[20]. There are diverse scientific and technological advances in the literature that provide computational models and finite element models focused on simulating the mammary gland for preclinical evaluation, prevention, training, diagnostic [21][22][23][24][25][26][27][28][29][30][31] or on analyzing the biomaterials used for implant reconstruction [14,15,32]. In the case of the most advanced computational models of a breast for the simulation of the anatomy is the anthropomorphic software breast phantom.…”

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confidence: 99%

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A Biomimetic Approach for Designing a Full External Breast Prosthesis: Post-Mastectomy

et al. 2018

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This work presents the design of a new breast prosthesis using the biomimetic technique for cases of complete mastectomy to address the problem of the increasing number of women diagnosed with breast cancer in Mexico who are candidates for a mastectomy. The designed prosthesis considers the morphology of a real breast regarding its internal structure to obtain authentic mobility and feel. In order to accomplish this, a model was obtained in 3D CAD using a coordinate measuring machine (CMM) that can be scalable without losing its qualities, and which can be used in any type of patient; afterwards, a finite element model was developed and a static analysis performed with suggested load cases to evaluate the sensitivity and naturalness of the prosthesis; and finally, a modal analysis was conducted. The results obtained in displacements and in distribution of stress for the load cases assessed are consistent with those of a real breast: there were smooth contours and there was natural mobility in the prosthesis designed by means of the biomimetic technique.

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Simulation of breast compression in mammography using finite element analysis: A preliminary study

Cited by 10 publications

References 22 publications

Optical breast atlas as a testbed for image reconstruction in optical mammography

Optical breast atlas as a testbed for image reconstruction in optical mammography

Mammographic density and its association with molecular subtype of breast cancer.

A Biomimetic Approach for Designing a Full External Breast Prosthesis: Post-Mastectomy

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