Adjusting the flow rate of an electronic coolant pump (ECP) over a wide range can cause significant internal pressure fluctuations, leading to vibration and noise. This study uses numerical simulation to compare pressure fluctuations at the backflow orifice and within the impeller of an ECP at various flow rates. The backflow creates periodic disturbances in the impeller inlet region. As the flow rate increases, the axial influence range of the backflow on the impeller inlet decreases, reducing the amplitude of pressure fluctuations by up to 7.9%. The characteristic frequencies of pressure fluctuations at the backflow orifice include the blade passing frequency and its first harmonic. Within the impeller, the pressure fluctuation amplitude increases with both flow direction and flow rate, with characteristic frequencies encompassing the rotational frequency, BPF, and its first harmonic. At low flow rates, the overall variation of pressure fluctuations inside the impeller shows an opposite trend compared to design and high flow rates. The impact of the rotational frequency on pressure fluctuations inside the impeller is significantly smaller at the design flow rate than at other flow rates. This study offers insights that can help optimize ECP design and enhance their operational performance.