The main goal of designing a multistage fiber amplifier is to achieve higher performance for long-haul optical transmission systems. In this paper, multistage triple-pass (TP) TDFAs are represented. Three types of TP-TDFA are modeled, optimized, and compared in the S-band for next-generation fiber optical communication systems. First, to examine the performance of these 3 types of TP-TDFAs, signal power, pump power, thulium-doped fiber (TDF) length, and thulium ion concentration were optimized in the input signal at the 1469 nm wavelength, which gives the highest gain value in the S-band, respectively. Second, the input signals in the 1444–1499 nm band gap were amplified by using these specified optimized values in all designs. Gain and noise figure values of all three types were obtained and analyzed by plotting separately for easy comparison. At the end of the study, all results were evaluated and all types were compared to determine the best TP-TDFA.