With the development of the economy and the innovation of technology, enterprises are eager to have higher, efficient, energy-saving and environmental protection technology applied in the cutting process. There are a lot of problems in the cutting process right now, For example, there will be uneven cutting section, Cutting dust debris splashing around causes environmental pollution and other problems. So, it is still necessary to constantly improve the cutting equipment. This paper studies the simulation of plasma cutting machine based on DELMIA. The cutting path in AUTOCAD is imported into DELMIA, and the cutting nozzle is simulated according to this path. At the same time, the second development of DELMIA is conducted based on VB language. The information of different steel plates can be automatically matched with the cutting nozzle type, cutting speed, etc., and is associated with the motion speed in DELMIA software. Seek the shortest cutting path, reduce the empty path, increase the effective cutting working time, so as to improve the cutting efficiency; And take into account environmental protection to reduce pollution and reduce noise.