2019
DOI: 10.3389/fchem.2019.00232
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Simultaneous and Ultrasensitive Detection of Foodborne Bacteria by Gold Nanoparticles-Amplified Microcantilever Array Biosensor

Abstract: Foodborne pathogens, especially bacteria, are explicitly threatening public health worldwide. Biosensors represent advances in rapid diagnosis with high sensitivity and selectivity. However, multiplexed analysis and minimal pretreatment are still challenging. We fabricate a gold nanoparticle (Au NP)-amplified microcantilever array biosensor that is capable of determining ultralow concentrations of foodborne bacteria including Escherichia coli O157:H7, Vibrio parahaemolyticus,… Show more

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Cited by 46 publications
(18 citation statements)
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“…In adsorption-based biosensors (e.g. SPR (Surface Plasmon Resonance), resistive graphene-based, CNT (Carbon NanoTube) or NWFET (NanoWire Field Effect Transistor), SAW (Surface Acoustic Wave), FBAR (thin Film Bulk Acoustic wave Resonator), microcantilever sensors) detection of the target analyte and measurement of its concentration are based on the change of a measurable parameter of the sensing element, caused by analyte adsorption on the active surface [21][22][23][24][25][26][27][28]. Namely, the adsorption leads to the change of some of the sensing element's physical parameters (e.g.…”
Section: Mathematical Models Of Sensor Temporal Responsementioning
confidence: 99%
“…In adsorption-based biosensors (e.g. SPR (Surface Plasmon Resonance), resistive graphene-based, CNT (Carbon NanoTube) or NWFET (NanoWire Field Effect Transistor), SAW (Surface Acoustic Wave), FBAR (thin Film Bulk Acoustic wave Resonator), microcantilever sensors) detection of the target analyte and measurement of its concentration are based on the change of a measurable parameter of the sensing element, caused by analyte adsorption on the active surface [21][22][23][24][25][26][27][28]. Namely, the adsorption leads to the change of some of the sensing element's physical parameters (e.g.…”
Section: Mathematical Models Of Sensor Temporal Responsementioning
confidence: 99%
“…The microcantilever array sensor enabled simultaneous determination of the multiple bacteria at concentrations as low as 1-9 cells mL −1 with a working range of three orders of magnitude. Hence, this strategy represents a significant advance in DNA-based pathogen detection due to its ultrasensitive, fast, and high-throughput fashion (Zheng et al, 2019).…”
Section: Static Modementioning
confidence: 99%
“…Electrochemical detection is another promising diagnostic method. Sensors capable of recognition of specific bacteria can base on protein and DNA detection as well on immunoassays [ 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 ]. Ahmed et al [ 37 ] proposed an electrochemical sensor for the Streptococcus pyogenes detection from human saliva.…”
Section: Introductionmentioning
confidence: 99%