2005
DOI: 10.1111/j.1540-8191.2005.200463.x
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Simultaneous Antegrade/Retrograde Normothermic Perfusion with Blood (Beating Heart) for Aortic Root Replacement in Acute Type-A Dissection of the Aorta

Abstract: A new technique of myocardial protection was utilized in performing surgery for acute type-A dissection involving the aortic valve, requiring replacement of the root. Simultaneous antegrade and retrograde perfusion of the heart with normothermic blood at high flows allows for safe and precise surgery, without concerns for the period of aortic clamping, since ischemia is eliminated altogether.

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Cited by 12 publications
(16 citation statements)
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“…We have routinely perfused the coronary sinus with mean pressures of 50 to 55 mmHg without consequences. In this series of patients, there was not a single coronary sinus injury, or observed edema of the myocardium due to simultaneous antegrade/retrograde perfusion 7 . Systematic de‐airing maneuvers were performed in all patients without any problem 14 …”
Section: Discussionmentioning
confidence: 88%
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“…We have routinely perfused the coronary sinus with mean pressures of 50 to 55 mmHg without consequences. In this series of patients, there was not a single coronary sinus injury, or observed edema of the myocardium due to simultaneous antegrade/retrograde perfusion 7 . Systematic de‐airing maneuvers were performed in all patients without any problem 14 …”
Section: Discussionmentioning
confidence: 88%
“…This is particularly important in patients with left ventricular hypertrophy, who may require complex procedures, with prolonged aortic cross‐clamping 4 . Beating heart valve surgery may offer some benefit over conventional hypothermic cardioplegic arrest, 5‐7 including continuous perfusion of the heart, less ischemia‐reperfusion injury, decreased need for inotropic support, decreased mechanical ventilation time, and fewer postoperative complications 6 …”
mentioning
confidence: 99%
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“…Another option is to perform the distal anastomosis using continuous myocardial perfusion by the retrograde route alone. This is well tolerated for the short period required to construct that anastomosis 16 . However, we do not recommend performing the entire aortic repair keeping the heart beating and perfused by the retrograde route alone.…”
Section: Methodsmentioning
confidence: 99%
“…Although beating heart surgery had been used in the early days of cardiac surgery, it was only recently that several surgical groups including ours [1,2] reported mitral valve surgery without cardioplegia. The operation is performed on a beating heart, minimizing or eliminating ischemia-reperfusion injury due to aortic cross-clamping and myocardial ischemia.…”
Section: Introductionmentioning
confidence: 99%