Simultaneous aortic aneurysm repair and colonic surgery

Oshodi, T O; Abraham, John S.; Kelly, J. F.

doi:10.1046/j.1365-2168.1999.00966.x

Cited by 8 publications

(2 citation statements)

References 4 publications

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“…Malignant tumors, most of which are colonic, are unexpectedly found in 4% to 5% of patients undergoing operation for aortic aneurysms. Although controversial, it has been recommended that the aneurysm procedure should be completed and the colon left alone in the presence of concomitant colonic pathology requiring resection and anastomosis [27][28][29][30]. There are several reasons for this policy, including contamination of the graft and absence of bowel preparation.…”

Section: Discussionmentioning

confidence: 99%

Effect of Ischemia/Reperfusion as a Systemic Phenomenon on Anastomotic Healing in the Left Colon

et al. 2000

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Intestinal ischemia/reperfusion provokes a local inflammatory response leading to a systemic inflammatory state. In this study we aimed to assess the effects of intestinal ischemia/reperfusion injury on anastomotic healing in the left colon with an intact vascular supply. A total of 94 Wistar albino rats were divided into three groups: sham-operated control (group I, n = 25), 30 minutes of intestinal ischemia/reperfusion (group II, n = 40), and 7-day allopurinol pretreatment and intestinal ischemia/reperfusion (group III, n = 29). After the reperfusion experiment, a segmental left colon resection and anastomosis were done. On postoperative days 3 and 7 anastomotic bursting pressure, anastomotic and operative complications, and intraabdominal adhesions were assessed. Mortality rates were 1/25, 16/40, and 4/29 for groups I, II, and III, respectively (p = 0.001). There was no difference among the groups for wound and anastomotic healing parameters evaluated by macroscopic criteria. On postoperative day 7 the mean bursting pressures were 220.3 +/- 18.5, 162.0 +/- 21.0, and 213.9 +/- 24.7 for groups I, II, and II, respectively (p = 0.000). Significantly dense adhesions were found in group II (p = 0.000). Allopurinol pretreatment prevented the effects of ischemia/reperfusion on anastomotic healing of the left colon. Intestinal/ischemia reperfusion causes impairment of anastomotic healing of the left colon. In addition to remote organ effects, reperfusion injury may affect anastomotic healing in the viscera with an intact vascular supply.

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Section: Discussionmentioning

confidence: 99%

Effect of Ischemia/Reperfusion as a Systemic Phenomenon on Anastomotic Healing in the Left Colon

et al. 2000

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“…[21][22][23] The final analysis included 24 articles. [3][4][5][6][7][9][10][11]17,[24][25][26][27][28][29][30][31][32][33][34][35][36][37] Characteristics of the studies included are shown in Table I. The studies were published between 1988 and 2014.…”

Section: Resultsmentioning

confidence: 99%

Management of concomitant abdominal aortic aneurysm and colorectal cancer

Kouvelos

Patelis

Antoniou

et al. 2016

Journal of Vascular Surgery

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Among different approaches, no significant differences in 30-day outcomes among patients treated in either two or one stage were evident. EVAR showed the lowest mortality and also diminished the delay between the two procedures in <2 weeks for a two-stage approach, although it has been associated with a significant risk for thrombotic events. The coexistence of AAA and CRC seems to favor the use of EVAR in treating those patients.

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