Simultaneous determination and toxicological assessment of penicillins in different water matrices

Tong, Lei; Wang, Yu; Hermo, M.P.; Barrón, D.; Barbosa, J.

doi:10.1007/s10646-014-1336-1

Cited by 9 publications

(1 citation statement)

References 35 publications

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“…This compound was only measured at low concentration (5 ng/L) in the GW of Mallorca Island (Rodríguez-Navas et al, 2013). The rest of investigated GW bodies located in Catalonia (Boy-Roure et al, 2018;Cabeza et al, 2012;Candela et al, 2016;Teijon et al, 2010;Tong et al, 2014a) and Cádiz (Corada-Fernández et al, 2017) were free of this compound (Table S1 of the Supplementary Material).…”

Section: Amoxicillinmentioning

confidence: 99%

Occurrence, fate and environmental risk assessment of the organic microcontaminants included in the Watch Lists set by EU Decisions 2015/495 and 2018/840 in the groundwater of Spain

Jurado

Walther

Díaz˗Cruz

2019

Science of The Total Environment

135

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This paper aims to review the existing occurrence data in Spanish groundwater (GW) for the emerging organic contaminants (EOCs) defined in the surface water Watch Lists of Decisions 2015/495/EU and 2018/840/EU since these contaminants are likely to reach GW bodies because surface waters show close interaction with GW. These two lists include 20 substances: 9 pesticides (5 neonicotinoids, 2 carbamates, 1 oxadiazole and 1 semicarbazone), 6 pharmaceuticals (diclofenac and 5 antibiotics), 3 estrogens, 1 UV filter (2-ethylhexyl-4-methoxycinnamate, EHMC) and 1 antioxidant (2,6-di-tertbutyl-4-methylphenol, BHT). Most of these substances are usually detected at low ng/L concentration range or not detected in the GW bodies of Spain. However, eventually they are reported at concentrations greater than 100 ng/L (e.g., imidacloprid, methiocarb, diclofenac, macrolide antibiotics, ciprofloxacin, EHMC and BHT).Consequently, it is required to set up drinking water standards, and/or GW threshold quality values because GW is a valuable water resource worldwide. Overall, GW is less contaminated than other water bodies, such as rivers, suggesting that aquifers possess a natural attenuation capacity and/or are less vulnerable than rivers to contamination.Nevertheless, the natural hydrogeochemical processes that control the fate and transformation of these substances during infiltration and in the aquifer have been barely investigated so far.The concentrations of the target EOCs are used to calculate hazard quotients (HQs) in the Spanish GW bodies as an estimation of their ecotoxicity and in order to compare somehow their chemical quality with respect to those of surface water. Due to the limited ecotoxicity data for most EOCs, HQs can only be calculated for few substances.The results pointed out the risk posed by the anti-inflammatory diclofenac towards Ceriodaphnia dubia (HQ = 21) and the medium risk associated to the antibiotic erythromycin for Brachionus calyciflorus (HQ = 0.46).

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Section: Amoxicillinmentioning

confidence: 99%

Occurrence, fate and environmental risk assessment of the organic microcontaminants included in the Watch Lists set by EU Decisions 2015/495 and 2018/840 in the groundwater of Spain

Jurado

Walther

Díaz˗Cruz

2019

Science of The Total Environment

135

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Occurrence, fate, and risk of the organic pollutants of the surface water watch List in European groundwaters: a review

et al. 2022

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Groundwater is the main source of freshwater in the European Union, yet freshwaters are polluted by organic contaminants if contaminants are not efficiently removed in wastewater treatment plants. Here we review the occurrence, fate, and risk assessment of organic contaminants included in the surface water watch list of the European groundwater bodies. This list includes 15 compounds: the hormones estrone, 17˗β˗estradiol and 17˗α˗ethinylestradiol; the pesticides methiocarb, metaflumizone, imidacloprid, thiacloprid, thiamethoxam, clothianidin and acetamiprid; and the antibiotics amoxicillin, ciprofloxacin, azithromycin, clarithromycin and erythromycin. We found that while contaminants commonly occur at low levels of few nanograms per L or are not detected in natural waters, there is an increasing number of reports displaying concentrations above 100 ng/L. Surface waters are commonly more contaminated than groundwater, suggesting that contaminants are removed in groundwater aquifers, e.g. by sorption or biodegradation. The estimated risk following water drinking by humans is higher for infants than for adults. Nonetheless, on the average, groundwater consumption does not pose a risk for human health at the reported groundwater concentrations. Risk assessment using fish, plants, algae, and invertebrates shows that only few species are impacted by contaminants, e.g. Americamysis bahia, Mysidopsis bahia, and Daphnia magna by pesticides; and the plant Lemna minor and the algae Microcystis aeruginosa by the antibiotics ciprofloxacin and erythromycin.

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Global development of the studies focused on antibiotics in aquatic systems from 1945 to 2017

Zheng

Cotner

Sato

et al. 2018

Environ Sci Pollut Res

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Antibiotics are used to fight diseases in humans and farm animals. Their residues, however, can enter aquatic environments and affect the resistance of non-target microbial strains, and the prevalence of antibiotic resistance genes (ARGs) potentially poses negative impacts on human health. In order to better understand how the studies of antibiotics have been conducted, we analyzed the publications on antibiotics in aquatic systems for the period of 1945-2017. We applied a bibliometric analysis method by coupling cluster analysis and network analysis. Results indicated that early research on antibiotics in water was mostly performed in America and Europe, while, in recent years, publications for the same subject were dominated by China and the USA. The majority of the articles were published in journal Chemosphere and the most representative subject categories of the seven sections were "Environmental science and ecology," "Chemistry," "Engineering," "Biochemistry and molecular biology," "Water resources," "Agriculture," and "Pharmacology and pharmacy." The most studied class of antibiotics was tetracyclines in wastewater. Antibiotic resistance, ARGs, Escherichia coli, and some mechanistic studies such as adsorption, toxicity, degradation, and kinetics were common topics in this field. ARGs present a major public health concern and much attention should be directed at the problems with antibiotics in the future studies of water.

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Simultaneous determination and toxicological assessment of penicillins in different water matrices

Cited by 9 publications

References 35 publications

Occurrence, fate and environmental risk assessment of the organic microcontaminants included in the Watch Lists set by EU Decisions 2015/495 and 2018/840 in the groundwater of Spain

Occurrence, fate and environmental risk assessment of the organic microcontaminants included in the Watch Lists set by EU Decisions 2015/495 and 2018/840 in the groundwater of Spain

Occurrence, fate, and risk of the organic pollutants of the surface water watch List in European groundwaters: a review

Global development of the studies focused on antibiotics in aquatic systems from 1945 to 2017

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