Simultaneous determination of bisphenol A-diglycidyl ether, bisphenol F-diglycidyl ether and their hydrolysis and chlorohydroxy derivatives in canned foods

Determination and occurrence of bisphenol A, bisphenol A diglycidyl ether, and bisphenol F diglycidyl ether, including their derivatives, in canned foodstuffs' from the Czech retail market

“…Also, BADGE·2HCl is coeluted with the third BFDGE isomer (o,o' configuration). These problems, in some cases potentially complicating the data evaluation, were earlier discussed also by other authors (Lintschinger & Rauter 2000). The calculation of the proportional contributions to the responses of individual analytes in the corresponding isomeric clusters is based on the specific response factors.…”

“…Following the first report updating the issue of bisphenols migration from can lacquers into preserved food (Biedermann et al 1996), numerous studies were carried out to monitor some of the mentioned migrants in canned food samples like various fish and seafood in oil (Biedermann et al 1996Bronz et al 1997;Roubtsova et al 1997;Biedermann & Grob 1998;Rauter et al 1999;Simoneau et al 1999;Hammarling et al 2000;Lintschinger & Rauter 2000;Theobald et al 2000;Berger et al 2001), and also various vegetables and fruits (Biedermann et al 1999a, b;Lintschinger & Rauter 2000). In a comprehensive survey published in the late 90s, the migration of bisphenols from various can lacquers and their distribution between the solid and liquid portions of the can content (Summerfield et al 1998) (Biedermann et al 1996;Biedermann & Grob 1998).…”

“…In the first step, RP-HPLC/FLD was utilised to identify the apparently contaminated samples, in the next phase the confirmation was carried out based on acetylation followed by analysis using NP-HPLC/FLD. In the case of inconsistency of the results obtained by these two approaches, NPLC fractions were collected and analysed by GC-MS. Lintschinger and Rauter (2000) used RP-HPLC with a binary mobile phase system consisting of methanol/water and acetonitrile/water to separate BADGE, BFDGE, and their derivatives. However, this approach did not enable a sufficient resolution BADGE·H 2 O and BADGE·H 2 O·HCl, an isocratic method of methanol/water was required to complete the separation.…”

Field‐amplified sample injection‐micellar electrokinetic capillary chromatography for the analysis of bisphenol A, bisphenol F, and their diglycidyl ethers and derivatives in canned soft drinks

“…The mobile-phase organic modifier has an important effect on the elution of diglycidylethers. For instance, Lintschinger and Rauter [20] reported a change in the elution order of BADGE·H 2 O and BADGE·HCl·H 2 O when methanol was used instead of acetonitrile; this effect is probably due to the relative hydrophobicity of both solvents. In methanol, BADGE·H 2 O appears before BADGE·HCl·H 2 O and BFDGE elutes between these compounds, which provides good resolution between the three compounds.…”

“…In methanol, BADGE·H 2 O appears before BADGE·HCl·H 2 O and BFDGE elutes between these compounds, which provides good resolution between the three compounds. In general, for the analysis of this family of compounds, methanol provides good chromatographic profiles for the different isomers of BFDGE and its derivatives [17,20]. Since, the purchase of a mass spectrometer is not always an affordable expense for some laboratories, the development of alternative cheap, fast and sensitive methods is needed.…”