Simultaneous determination of mixtures of nitrophenols using multivariate curve resolution-alternating least squares

Abstract

A simple procedure for the quantitative determination of mixtures of nitrophenols pollutants in environmental and biological samples based on continuous spectrophotometric acid-base titrations and multivariate curve resolution has been proposed. The procedure simultaneously takes into account the spectroscopic and acidbase properties of the nitrophenols, which leads to a higher selectivity. The quantitative determination of analyte in the presence of unknown and uncalibrated interferences is a general benefit of the method. Moreover, only one single synthetic standard containing of the analyte of interest is enough to perform the analysis. Because of the rank-deficiency phenomena, the pure spectra and concentration profiles of the species of interest can only be recovered through matrix augmentation. Even in the presence of the rank deficiencies, in most cases accurate quantitation with relative errors in prediction lower than 5 % was obtained. The percent recoveries obtained (92-108 %) were satisfactory.

Design, synthesis, and characterization of 2,2-bis(2,4-dinitrophenyl)-2-(phosphonatomethylamino)acetate as a herbicidal and biological active agent

“…He has concluded that the phosphorus contains herbicides (e.g., glyphosate) can stimulate soil microbial growth [40]. Biodegradation of nitro group-based herbicides can easily do in the presence of PGPR by converting the nitro group into amine group [18,22,25,63].…”

“…Various author have noticed that many amino acid and nitro derivatives have medicinal values including the antimicrobial and antifungal activities [15,18,21,22,24,25,44,52,63].…”

“…Moreover, many amino acid and nitro derivatives have been reported to have antimicrobial activities [15,18,21,22,24,25,44,52,55,63]. Therefore, the synthesized molecule 1 was also investigated for its potential as antimicrobial agent.…”

Evaluation of conversion during the synthesis of aluminum (III) methacrylate-based copolymers using Raman spectroscopy and multivariate curve resolution

“…Basically, MCR-ALS is characterized by a bilinear decomposition of an original data matrix (D) into two matrices [31][32][33][34][35][36][37][38][39][40][41][42][43]: i) a matrix corresponding to the concentration profiles (C) and; ii) a second matrix related to the pure spectra profiles (S). MCR model can be expressed as D = CS T + ε, where the matrix D (dimensions m different individual spectra by n intensities measured at each spectral points) is approximated by the product of the matrix C (dimensions k components in the different by m rows of the data matrix) and matrix S T (transpose of matrix pure spectral profiles of dimensions k components by n columns of the original data matrix); and ε is the matrix of residuals (dimensions m different individual spectra by n intensities) containing the information not explained by the model.…”

“…MCR-ALS is extensively employed in several technological issues related with the quantitation antibacterial agents presented water samples [44], determination of furosemide in the presence of interfering agent (anti-inflammatory flufenamic acid) [45], quantitative determination of sulfur [32], sulfonamide drugs in biomedical analysis [46], mixtures of nitrophenols pollutants in environmental and biological samples [34], proteinaceous binders in medieval paints [37], antioxidants (butylatedhydroxytoluene and N,N′-di-secbutyl-p-phenylenediamine) in biodiesel blends [41] and concentration profiles in milk lactic acid fermentation [33]; enzymatic determination of levodopa and carbidopa in pharmaceuticals [47], measurements of the relative amounts of different iron oxide and oxyhydroxides present in the passive films [48], interpretation of the kinetic behavior of the photochemical degradation process of decabromodiphenyl ether [43] and photodynamics of salicylidene aniline in ultrafast competitive photoreactions [38].…”