Simultaneous determination of nine fluoroquinolones in egg white and egg yolk by liquid chromatography with fluorescence detection

Determinaton of enrofloxacin and ciprofloxacin in albumin and freeze-dried-eggs by liquid chromatography with fluorescence detection

“…Due to the real risk of occurrence of ENR and CIP residues in processed eggs, it was necessary to develop a method for determination of ENR and CIP residues in albumin and freeze-driedeggs. There are many analytical methods for determination of fluoroquinolones in hen egg yolk (5,7,8,9,16) and albumen (4,20), but none of them covered the ENR and CIP determination in processing eggs.…”

“…Some methods use double extraction procedure with different organic solution (8), triple extraction procedure (4), organic extraction step after then organic purification of sample and re-extraction (16), extraction with three compounds composition, evaporation and organic purification of extract again (20). To optimise the sample extraction procedure, methanol, methanol with acidic buffers, acetonitrile, acetonitrile with ammonium, and different acids were tested.…”

Preparation of high-affinity rabbit monoclonal antibodies for ciprofloxacin and development of an indirect competitive ELISA for residues in milk

“…However, these methods are complicated, timeconsuming, and specificity-lacking (Kurittu et al, 2000). Instrumental methods, including liquid chromatography-mass spectrometry (LC-MS) and highperformance liquid chromatography (HPLC) (Johnston et al, 2002;van Vyncht et al, 2002;EspinosaMansilla et al, 2005;Toussaint et al, 2005a;2005b;Zeng et al, 2005), are the most current widely used methods for CPFX residues detection. These methods are sensitive and highly specific, but they require expensive equipment, large volumes of solvents, and highly trained individuals for operating complicated instruments, with time-consuming sample cleanup processes.…”

Integration of phase separation with ultrasound-assisted salt-induced liquid–liquid microextraction for analyzing the fluoroquinones in human body fluids by liquid chromatography

“…The widespread application of fluoroquinolones (FQs) in human and food-producing animals has increased human health concerns because of induced pathogen resistance and possible allergic hypersensitivities in humans [1][2][3][4][5][6]. Previous research has demonstrated that low amounts of FQs were often found in plasma and their main excretion pathway in urine [5,6].…”