Simultaneous electro-catalytic oxidative determination of ascorbic acid and folic acid using Fe3O4 nanoparticles modified carbon paste electrode

Kingsley, Mal Phebe; Desai, Purvi B.; Srivastava, Ashwini K.

doi:10.1016/j.jelechem.2014.12.039

Cited by 63 publications

(17 citation statements)

References 41 publications

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“…The analysis and determination of pharmaceutical compounds plays a key role in examining its purity and possible consequences on the treatment method (Afshar et al 2020). Folic acid (FA) is an important water-soluble vitamin and an essential hematogenic agent which acts as coenzyme to regulate the generation of ferroheme (Kingsley et al 2015). It also helps in the synthesis and methylation of DNA (D'Souza et al 2017).…”

Section: Introductionmentioning

confidence: 99%

Electrochemical investigations and theoretical studies of biocompatible niacin-modified carbon paste electrode interface for electrochemical sensing of folic acid

et al. 2021

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The modified electrode–analyte interaction is critical in establishing the sensing mechanism and in developing an electrochemical sensor. Here, the niacin-modified carbon paste electrode (NC/CPE) was fabricated for electrochemical sensing applications. The two stable structures of the niacin were optimized and confirmed by the absence of negative vibrational frequency, at B3LYP and B3LYP-GD3BJ level and 6–311 g** basis set. The physical and quantum chemical quantities were used to explain the molecular stability and electronic structure-related properties of the niacin. The natural bond orbital (NBO) analysis was performed to disclose the donor–acceptor interactions that were a critical role in explaining the modifier–analyte interaction. The fabricated NC/CPE was used for the determination of folic acid (FA) in physiological pH by cyclic voltammetry (CV) method. The limit of detection (LOD) for FA at NC/CPE was calculated to be 0.09 µM in the linear concentration range of 5.0 µM to 45.0 µM (0.2 M PBS, pH 7.4) by CV technique. The analytical applicability of the NC/CPE was evaluated in real samples, such as fruit juice and pharmaceutical sample, and the obtained results were acceptable. The HOMO and LUMO densities are used to identify the nucleophilic and electrophilic regions of niacin. The use of density functional theory-based quantum chemical simulations to understand the sensory performance of the modifier has laid a new foundation for fabricating electrochemical sensing platforms.

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Section: Introductionmentioning

confidence: 99%

Electrochemical investigations and theoretical studies of biocompatible niacin-modified carbon paste electrode interface for electrochemical sensing of folic acid

et al. 2021

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“…Among these diverse magnetic nanomaterials reported before, Fe 3 O 4 NPs have been studied extensively because of their excellent magnetism, biocompatibility, and especially, highly effective electrocatalytic activity. For example, Kingsley et al fabricated Fe 3 O 4 nanoparticle-(NP-) modified carbon paste electrode to detect ascorbic acid (AA) and folic acid (FA) at the same time, with the detection limits of 2.51 × 10 -7 and 2.01 × 10 -9 M, respectively [6]. Qu and coworkers established a novel hydrogen peroxide (H 2 O 2 ) sensor using Fe 3 O 4 NPs/chitosan composite-modified electrode, which could electrocatalyze the reduction of H 2 O 2 with a detection limit of 1.53 × 10 -6 M [7].…”

Section: Introductionmentioning

confidence: 99%

A Novel Nonenzymatic Hydrogen Peroxide Sensor Based on Magnetic Core-Shell Fe3O4@C/Au Nanoparticle Nanocomposite

Xiao

Tian

Sun

et al. 2021

International Journal of Analytical Chemistry

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Fe3O4@C/Au nanoparticle (AuNP) nanocomposites were prepared through electrostatic adsorption of AuNPs onto PDDA-functionalized core/shell Fe3O4@C magnetic nanospheres, which had been synthesized by a facile solvothermal method. The morphology and composition of the nanocomposites were characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), Fourier transform infrared (FT-IR), etc. Moreover, highly electrocatalytic activity to the reduction of hydrogen peroxide (H2O2) was also exhibited on the Fe3O4@C/AuNP-modified indium tin oxide (ITO) electrode. The effect of solution pH and the modification amount of Fe3O4@C/AuNPs on the performance of electrocatalytic H2O2 reduction was investigated. Under the optimal conditions, the catalytic current showed a linear relationship with the increase of H2O2 concentration in the range of 0.007–15 mM and a detection limit of 5 μM. The H2O2 sensor showed high selectivity for H2O2 detection, which could effectively resist the interference of ascorbic acid (AA), uric acid (UA), and citric acid (CA). Finally, the H2O2 sensor was used in the real fetal bovine serum to detect H2O2 and obtained satisfactory results with the recovery values ranging from 95.14 to 103.6%.

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“…Folic acid (FA) is a B-group vitamin that plays a significant role in the biological functions of cell metabolism [33,34]. Its deficiency in our body causes many disorders, including increased risk of colorectal cancer, neural tube defects, hypomethylation, and triggering proto-oncogene expression in cancer [35][36][37]. Supplements in different quantities of FA are available to treat FA deficiency and hence its quantitative determination is necessary to control the quality of pharmaceutical and food products.…”

Section: Introductionmentioning

confidence: 99%

Rapid One-Pot Synthesis of Polydopamine Encapsulated Carbon Anchored with Au Nanoparticles: Versatile Electrocatalysts for Chloramphenicol and Folic Acid Sensors

Mani

Balamurugan

Huang

2020

IJMS

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Designing and engineering nanocomposites with tailored physiochemical properties through teaming distinct components is a straightforward strategy to yield multifunctional materials. Here, we describe a rapid, economical, and green one-pot microwave synthetic procedure for the preparation of ternary nanocomposites carbon/polydopamine/Au nanoparticles (C/PDA/AuNPs; C = carbon nanotubes (CNTs), reduced graphene oxide (rGO)). No harsh reaction conditions were used in the method, as are used in conventional hydrothermal or high-temperature methods. The PDA unit acts as a non-covalent functionalizing agent for carbon, through π stacking interactions, and also as a stabilizing agent for the formation of AuNPs. The CNTs/PDA/AuNPs modified electrode exhibited excellent electrocatalytic activity to oxidize chloramphenicol and the resulting sensor exhibited a low detection limit (36 nM), wide linear range (0.1–534 μM), good selectivity (against 5-fold excess levels of interferences), appreciable reproducibility (3.47%), good stability (94.7%), and practicality (recoveries 95.0%–98.4%). Likewise, rGO/PDA/AuNPs was used to fabricate a sensitive folic acid sensor, which exhibits excellent analytical parameters, including wide linear range (0.1–905 μM) and low detection limit (25 nM). The described synthetic route includes fast reaction time (5 min) and a readily available household microwave heating device, which has the potential to significantly contribute to the current state of the field.

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Simultaneous electro-catalytic oxidative determination of ascorbic acid and folic acid using Fe3O4 nanoparticles modified carbon paste electrode

Cited by 63 publications

References 41 publications

Electrochemical investigations and theoretical studies of biocompatible niacin-modified carbon paste electrode interface for electrochemical sensing of folic acid

Electrochemical investigations and theoretical studies of biocompatible niacin-modified carbon paste electrode interface for electrochemical sensing of folic acid

A Novel Nonenzymatic Hydrogen Peroxide Sensor Based on Magnetic Core-Shell Fe3O4@C/Au Nanoparticle Nanocomposite

Rapid One-Pot Synthesis of Polydopamine Encapsulated Carbon Anchored with Au Nanoparticles: Versatile Electrocatalysts for Chloramphenicol and Folic Acid Sensors

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