Simultaneous electrochemical detection of oxygen (O2) and hydrogen peroxide (H2O2) in neutral media

Gotti, Guillaume; Evrard, David; Gros, Pierre

doi:10.1016/j.ijoes.2023.100262

Cited by 2 publications

(1 citation statement)

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“…The GC electrode exhibits a narrower electrochemical window compared to the BDD electrode. Consequently, the analysis range is restricted, and the oxidation of water impedes the detection of compounds with high oxidation potentials [54]. Analyzing compounds with potentials involving reduction is, to our knowledge, impossible due to the reduction of dissolved oxygen [55].…”

Section: Electrode Geometrymentioning

confidence: 99%

The High-Precision Liquid Chromatography with Electrochemical Detection (HPLC-ECD) for Monoamines Neurotransmitters and Their Metabolites: A Review

Guiard,

Gotti

2024

Molecules

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This review highlights the advantages of high-precision liquid chromatography with an electrochemical detector (HPLC-ECD) in detecting and quantifying biological samples obtained through intracerebral microdialysis, specifically the serotonergic and dopaminergic systems: Serotonin (5-HT), 5-hydroxyindolacetic acid (5-HIAA), 3,4-dihydroxyphenylacetic acid (DOPAC), dopamine (DA), 3-metoxytryptamin (3-MT) and homovanillic acid (HVA). Recognized for its speed and selectivity, HPLC enables direct analysis of intracerebral microdialysis samples without complex derivatization. Various chromatographic methods, including reverse phase (RP), are explored for neurotransmitters (NTs) and metabolites separation. Electrochemical detector (ECD), particularly with glassy carbon (GC) electrodes, is emphasized for its simplicity and sensitivity, aimed at enhancing reproducibility through optimization strategies such as modified electrode materials. This paper underscores the determination of limits of detection (LOD) and quantification (LOQ) and the linear range (L.R.) showcasing the potential for real-time monitoring of compounds concentrations. A non-exhaustive compilation of literature values for LOD, LOQ, and L.R. from recent publications is included.

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Section: Electrode Geometrymentioning

confidence: 99%