Simultaneous extraction and determination of sulfadiazine and trimethoprim in medicated fish feed by high-performance liquid chromatography

Determination of five sulfonamides in medicated feedingstuffs by liquid chromatography with ultraviolet detection

“…Highly sensitive HPLC tandem mass spectrometry detection is associated with a high sensitivity but also with expensive equipment. Thus, HPLC-UV analysis is a simple and low-cost technique; however, it involves appropriate sample preparation step (8,10,13,17,30). Furthermore, no papers were found concerning five sulfonamides analysis in feedingstuffs in the range of concentrations used in this study.…”

“…The majority of techniques for sulfonamide detection in feedingstuffs described in recent papers most commonly use chromatographic methods. These methods comprise thin-layer chromatography (TLC) (5), enzyme immunoassay (EIA) (20,27), high performance liquid chromatography (HPLC) with ultraviolet (UV) detection (8,10,13,17,25,26,28), HPLC-UV in premix (28,29), HPLC with diode array detector (DAD) (1,11), HPLC-DAD in premix (2), HPLC with fluorescence detector (FLD) (13,2), HPLC connected to mass spectrometry (MS) (3,14,15,18,19,23), and micellar electrokinetic capillary chromatography (MEKC) with UV detection (12). The study of the literature allowed us to select and successfully optimise the chromatographic method with UV detection as a procedure, which can be easily implemented by any laboratory.…”

Permanganate Oxidation of Sulfadiazine: Analytical Method Development and Kinetic Study

“…Metal complexes of sulfadizine was also exploited as a therapeutic agent, zinc sulfadizine is used to prevent bacterial infection in burned animal 4 . There are several ISSN Print: 2229-7928 ISSN Online: 2230-7532 methods reported for the estimation of sulfadiazine, they include HPLC [5][6][7][8][9] in addition to the UV detector Mass spectroscopic determination was also employed in the determination of sulfadiazine [10][11][12] . Spectrophotometric method was also applied for the estimation of sulfadiazine 1,13 continuous flow spectrophotometric 14 and flow injection method 15 for determination of sulfadiazine is also available in the literature.…”

Sulfadiazine-Potentiometric Sensors for Flow and Batch Determinations of Sulfadiazine in Drugs and Biological Fluids

“…8 The United States Pharmacopoeia (USP) proposes a chromatographic separation before UV quantification of SDZ. 9 Other methods for SDZ determination are meant for the analysis of food [10][11][12][13][14][15][16][17][18][19][20] or feeding stuffs, 21 biological fluids, [22][23][24][25][26][27] or environmental samples. [28][29][30][31] These concern more complex and high cost procedures, unsuitable for the routine control of formulated pharmaceuticals.…”