Simultaneous investigations of maternal cardiac output and fetal blood flow during hypervolemic hemodilution in preeclampsia — preliminary observations

Siekmann, U.; Heilmann, L.; Klosa, W.; Quaas, L.; Schillinger, H.

doi:10.1515/jpme.1986.14.1.59

Cited by 18 publications

(3 citation statements)

References 16 publications

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“…The elevated hydrostatic pressure in the intervillous space, induced by PVE, may be the mechanism underlying the net flow of water into the fetal circulation. Our data are at variance with a previous study34 in which a significant increase in UV volume flow was observed after maternal hemodilution with 500 mL dextran.…”

Section: Discussioncontrasting

confidence: 99%

The impact of maternal plasma volume expansion and antihypertensive treatment with intravenous dihydralazine on fetal and maternal hemodynamics during pre‐eclampsia: a clinical, echo‐Doppler and viscometric study

Boito

Struijk

Pop

et al. 2004

Ultrasound in Obstet & Gyne

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Section: Discussioncontrasting

confidence: 99%

The impact of maternal plasma volume expansion and antihypertensive treatment with intravenous dihydralazine on fetal and maternal hemodynamics during pre‐eclampsia: a clinical, echo‐Doppler and viscometric study

Boito

Struijk

Pop

et al. 2004

Ultrasound in Obstet & Gyne

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“…For preeclampsia complicated with hemo,concentration, hypervolemic hemodilution ha! ; demonstrated benefits for the fetus ( 17). However, small changes in viscosity do not appear to influ.ence the flow velocity waveform in the maternal circulation (1 8).…”

Section: Discussionmentioning

confidence: 99%

Relationship between acute fetal distress and maternal‐placental‐fetal circulations in severe preeclampsia

Yang

Wang

1995

Acta Obstet Gynecol Scand

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“…Volume expansion improves fetal and maternal blood flow rates [9] and tends to reduce the raised arterial pressure [10]. In healthy humans, however, aggressive volume loading impairs lung function [11], and PE is a risk factor for the development of pulmonary oedema [12].…”

Section: Introductionmentioning

confidence: 99%

Distribution and elimination of crystalloid fluid in pre-eclampsia

Drobin

Hahn

2004

Clinical Science

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Pre-eclampsia (PE) is a disease of pregnancy associated with peripheral oedema and hypovolaemia, but few details are known about how women with PE handle a volume load of crystalloid fluid compared with healthy pregnant women. To study this issue, Ringer's acetate solution (12.5 ml/kg of body weight) was given by intravenous infusion over 30 min to eight women with PE and to eight healthy pregnant women matched with respect to gestational week (mean, 34 weeks). Venous blood was sampled and excreted urine was collected over 90 min to study the time course of the volume expansion by means of volume kinetic analysis. The results show that the size of the central body fluid space expanded by the infused fluid was smaller in PE (mean, 2940 ml compared with 4240 ml respectively; P<0.04), and the clearance constants for distribution (100 ml/min compared with 43 ml/min; P<0.04) and elimination (125 ml/min compared with 36 ml/min; P<0.02) were higher in the women with PE than in the controls. Less excess volume accumulated in the central body fluid space in the presence of PE, whereas the rates of distribution and elimination were higher during and for 15 min after the infusion. It is concluded that Ringer's acetate solution fluid is both distributed and eliminated faster in women with PE than in matched pregnant controls.

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Simultaneous investigations of maternal cardiac output and fetal blood flow during hypervolemic hemodilution in preeclampsia — preliminary observations

Abstract: Siekmann et al., Maternal cardiac output and fetal blood flow in pre-eclampsia 59

Cited by 18 publications

References 16 publications

The impact of maternal plasma volume expansion and antihypertensive treatment with intravenous dihydralazine on fetal and maternal hemodynamics during pre‐eclampsia: a clinical, echo‐Doppler and viscometric study

The impact of maternal plasma volume expansion and antihypertensive treatment with intravenous dihydralazine on fetal and maternal hemodynamics during pre‐eclampsia: a clinical, echo‐Doppler and viscometric study

Relationship between acute fetal distress and maternal‐placental‐fetal circulations in severe preeclampsia

Distribution and elimination of crystalloid fluid in pre-eclampsia

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