Simultaneous ^99mTc/¹¹¹In SPECT image reconstruction using convolution based forced detection

A modified TEW approach to scatter correction for In‐111 and Tc‐99m dual‐isotope small‐animal SPECT

“…The images for standard TEW, modified TEW, and no SC were separately assessed, and used as s3(i) in Eq. (13). A perfect agreement between the model and the cross talk-corrected image would result in an error of 0.…”

“…Cross talk correction methods have been developed for clinical imaging based on convolution subtraction, 6 energy-window subtraction, 7,8 and modeling approaches. [9][10][11][12][13] The accuracy of these methods for small-animal cardiac SPECT imaging has not been evaluated. The modeling methods tend to be the most accurate, but also the most computationally intensive.…”

Simulation-based reconstruction of absolute activities from the99mTc/111In dual-isotope SPECT/CT: phantom experiments and imaging of neuroendocrine tumors

“…Several attempts have been made to improve the quality of 99m Tc images reconstructed from simultaneous 99m Tc/ 111 In DI-SPECT studies. In particular, Monte Carlo (MC) simulations (Cervo andMoore 2011, Karamat andFarncombe 2011), triple energy window (TEW) technique (Feng and Penney 2002, Zhu et al 2007, Timmins and Wells 2012, convolution method (Feng and Penney 2002) and effective source scatter estimation (Du and Frey 2008) have been investigated. In comparative analyses, the superiority of MC based approaches over TEW was observed (Cervo andMoore 2011, Karamat andFarncombe 2011).…”

“…In particular, Monte Carlo (MC) simulations (Cervo andMoore 2011, Karamat andFarncombe 2011), triple energy window (TEW) technique (Feng and Penney 2002, Zhu et al 2007, Timmins and Wells 2012, convolution method (Feng and Penney 2002) and effective source scatter estimation (Du and Frey 2008) have been investigated. In comparative analyses, the superiority of MC based approaches over TEW was observed (Cervo andMoore 2011, Karamat andFarncombe 2011). Still, there are very few published results on the accuracy of the reconstructed absolute activities of both isotopes.…”

An Iterative-Triple-Energy Window Approach to Cross-Talk Correction in Quantitative Small Animal Tc-99m and In-111 Single Photon Emission Computer Tomography

“…In standard forced detection, photons at each Monte-Carlo-determined scatter point are forced towards the detector. Convolution-based forced detection has built upon this to provide an appropriate model with lower noise than a fully-Monte-Carlo method [51,52,53]. It works by stochastically forcing photons to the detector after each scattering event [21].…”