Simultaneous lymphoma and squamous cell carcinoma presenting as a neck lump

Millwaters, Michael; Khan, Noor Ahmad; Halfpenny, W.

doi:10.1016/j.bjoms.2006.12.010

Cited by 12 publications

(2 citation statements)

References 4 publications

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“… 15 However, the simultaneous presence of a primary lymphoid malignancy and OSCC is extremely rare, with only a few cases reported in the literature. 16 – 18 …”

Section: Discussionmentioning

confidence: 99%

Oral squamous cell carcinoma with synchronous follicular lymphoma: A rare case report

Binmadi,

Subahi,

Alsharif

et al. 2024

SAGE Open Medical Case Reports

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The occurrence of oral squamous cell carcinoma synchronously with lymphoma arising primarily in cervical lymph nodes is rare. Here, we report a case representing an infrequent finding. A 66-year-old male who was diagnosed with right mandibular squamous cell carcinoma and was subsequently found to have a nodal follicular lymphoma as a second malignancy. The patient underwent surgical resection for the oral squamous cell carcinoma with right selective neck dissection. The multidisciplinary team’s postoperative treatment strategy involved adjuvant radiotherapy for the oral squamous cell carcinoma, while adopting a close follow-up approach for the follicular lymphoma. After an 18-month follow-up, there were no evidence of disease progression. This case report highlights the diagnostic challenges of synchronous primary malignancies occurring in the head and neck region. It also underscores the importance to conduct a comprehensive clinical and histopathological examination to rule out the possibility of synchronous neoplasms.

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“… 15 However, the simultaneous presence of a primary lymphoid malignancy and OSCC is extremely rare, with only a few cases reported in the literature. 16 – 18 …”

Section: Discussionmentioning

confidence: 99%

Oral squamous cell carcinoma with synchronous follicular lymphoma: A rare case report

Binmadi,

Subahi,

Alsharif

et al. 2024

SAGE Open Medical Case Reports

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“…Similarly, a patient with concurrent oropharyngeal SCC and nasopharyngeal malignant lymphoma was reported by Watanabe et al [ 10 ]. Kader et al [ 11 ] identified eight patients with low-grade lymphoma and metastatic lymph nodes in the head area from primary cutaneous SCC, highlighting the diagnostic challenge. Millwaters et al [ 12 ] made note of the diagnostic difficulty in a patient who was initially treated for malignant lymphoma but persistent cervical lymphadenopathy revealed the second primary SCC.…”

Section: Discussionmentioning

confidence: 99%

Is There an Association between a Tonsillar Diffuse Large B-Cell Lymphoma Arising after a Neck Squamous Cell Carcinoma of Occult Primary? A Case Report and Extensive Literature Review

Tatsis,

Niakou,

Paraskevopoulos

et al. 2024

Hematology Reports

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Objectives: The aim of this review is to focus on the possibility of patients with squamous cell carcinoma to develop a second primary disease such as DLBCL, perhaps because of the irradiation of the head and neck area. Materials and methods: A case of an 89-year-old man is reported, who initially underwent surgical and complementary treatment for neck squamous cell carcinoma of occult primary and later for tonsillar diffuse large B-cell non-Hodgkin lymphoma. Results: The second primary was considered a recurrence in the neck of the original cancer of unknown primary, so a new surgical management was decided. The final pathology report described a diffuse large B-cell non-Hodgkin lymphoma. Conclusions: The importance of maintaining follow-ups for patients with occult primary cancers who are at an elevated risk of developing a metastasis or a second primary carcinoma outbreak is highlighted.

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Simultanes Plattenepithelkarzinom und follikuläres Lymphom der Tonsille

Albers

Hummel

Keilholz

et al. 2010

HNO

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Squamous cell carcinoma of the head and neck is the most common neoplasia in the head and neck area followed by malignant lymphoma. Here we describe for the first time the synchronous manifestation of a squamous cell carcinoma and a follicular lymphoma of the palatine tonsil. Histomorphologic and etiopathogenetic characteristics are described and discussed on the basis of the current literature. The coincidence of a lymphoma and a squamous cell carcinoma in the head and neck area is an oncologic rarity as well as an interdisciplinary diagnostic and therapeutic challenge.

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Simultaneous lymphoma and squamous cell carcinoma presenting as a neck lump

Cited by 12 publications

References 4 publications

Oral squamous cell carcinoma with synchronous follicular lymphoma: A rare case report

Oral squamous cell carcinoma with synchronous follicular lymphoma: A rare case report

Is There an Association between a Tonsillar Diffuse Large B-Cell Lymphoma Arising after a Neck Squamous Cell Carcinoma of Occult Primary? A Case Report and Extensive Literature Review

Simultanes Plattenepithelkarzinom und follikuläres Lymphom der Tonsille

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